Life in These Hawaiian Islands

Trade Winds, Tsunamis, and the Coconut Wireless


Leave a comment

Candida

http://kylejnorton.blogspot.ca/2015/03/the-research-paper-of-reader-guide-to_10.html

Tuesday, 10 March 2015
The research paper of Reader Guide To Cure Candidiasis: Some life threatening implications of candida overgrowth

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

What is Candida Albicans
Candida albicans is a member of a large group of micro organism whose cells contain complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and mold(6) that live among the gut flora in the human mouth and gastrointestinal tract. In fact, under normal circumstances, Candida albicans that does not cause harmful effects, but overgrowth results in candidiasis. Non-albicans Candida (NAC) species cause 35-65% of all candidaemias in the general patient population(1). According to joint study, in many cases, biofilm(microorganisms with cells stick to each other on a surface) formation(7) gene mutations(8) and overexpression of genes(9)(10) are often associated with increased Candida resistance toward antifungal agents.

Candida albicans consequences
Some life threatening implication of candida overgrowth
1. Toxic shock syndrome(TSS)
Candida overgrowth can cause toxic shock syndrome (TSS)(157), a potentially fatal illness by producing toxins to suppress the immune system(158)(159), leading to infection cause of high fever, accompanied by confusion, extreme fatigue and weakness, headache, severe diarrhea, sore throat, vomiting, widespread red rash, coma(161), and multiple organ failure(160).

2. Scalded skin syndrome (SSS)
Scalded skin syndrome is defined as a condition of skin infection caused of damage to the skin with marked shedding due to toxins(162) released by candida in suppressing the immune system(162). Depending its severity, it can causes bloodstream infection(163) and electrolyte imbalance, involved in regulate myocardial and neurological function(164), fluid balance(165), oxygen delivery, etc., resulting in high morbidity and mortality(166).

3. Candida and chronic diseases
a. Irritable Bowel Syndrome (IBS)(167)(168)
As the condition worsen, candida takes advantage of weakness immune system and imbalances in the digestive system, allowing fungus to overrun the digestive tracts(169), leading to gases which irritate the intestinal and stomach linings(171) cause of pain(170)(172).

b. Chronic Sinusitis(173)
As candida growth occurs in the sinus cavities(173), it causes fungal serious infections, with symptoms of nasal congestion, facial pain, pressure, congestion, or fullness, reduced or absent sense of smell. Both chronic and acute fungal sinusitis require immediate treatment(174).

c. Fibromyalgia
Fibromyalgia syndrome is a chronic condition that causes intense pain in various places around the body, including muscles, connective tissues and joints, as well as a host of other symptoms, as a result of production of mycotoxins by overgrowth candida(175), causing autoimmune diseases(143)(144)(136) by triggering inflammation in the intestinal tract(151). Fibromyalgia syndrome affects more than 6 million people in the United States.

d. Chronic Fatigue Syndrome
Chronic fatigue syndrome (CFS) is defined as a health condition of persistent fatigue unrelated to exertion, it interferes with the patient daily activity, causing trouble staying on top of their responsibilities at home and on the job, etc.(176) due to production of mycotoxins by overgrowth candida(177)(178), triggering inflammation(179) in the intestinal tract. Symptoms of chronic fatigue syndrome include headache, tender lymph nodes, fatigue, weakness, muscle, joint aches, inability to concentrate,(180) etc.

e. Thrush
Thrush is defined as condition of infection of the mouth caused by over growth candida fungus(181)(182).

f. Eczema, or Atopic Dermatitis
Eczema is a general term for many types of skin inflammation (dermatitis). The most common form of eczema is atopic dermatitis in some case caused by over growth of candida(183)(184) as a result of immune suppressive factors(185).

g. Etc.
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to home page http://kylejnorton.blogspot.ca/

References
(1) Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance by Krcmery V1, Barnes AJ.(PubMed)
(2) Pathogenicity and drug resistance in Candida albicans and other yeast species. A review by Mishra NN1, Prasad T, Sharma N, Payasi A, Prasad R, Gupta DK, Singh R.(PubMed)
(3) Multidrug resistance in yeast Candida by Prasad R1, Kapoor K.(PubMerd)
(4) New evidence that Candida albicans possesses additional ATP-binding cassette MDR-like genes: implications for antifungal azole resistance. by Walsh TJ1, Kasai M, Francesconi A, Landsman D, Chanock SJ.(PubMed)
(5) Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.by Sanglard D1, Kuchler K, Ischer F, Pagani JL, Monod M, Bille J.(PubMed)
(6) Structural analysis of phospho-D-mannan-protein complexes isolated from yeast and mold form cells of Candida albicans NIH A-207 serotype A strain by Shibata N1, Fukasawa S, Kobayashi H, Tojo M, Yonezu T, Ambo A, Ohkubo Y, Suzuki S.(PubMed)
(7) The effect of antifungal combination on transcripts of a subset of drug-resistance genes in clinical isolates of Candida species induced biofilms by Ibrahim NH1, Melake NA2, Somily AM3, Zakaria AS4, Baddour MM5, Mahmoud AZ6(PubMed)
(8) Antifungal drug resistance in pathogenic fungi. by Vanden Bossche H1, Dromer F, Improvisi I, Lozano-Chiu M, Rex JH, Sanglard D.(PubMed)
(9) The genetic basis of fluconazole resistance development in Candida albicans by Morschhäuser J1.(PubMed)
(10) A proteomic approach to understanding the development of multidrug-resistant Candida albicans strains by Kusch H1, Biswas K, Schwanfelder S, Engelmann S, Rogers PD, Hecker M, Morschhäuser J.(PubMed)
(157)Effect of strain of Staphylococcus aureus on synergism with Candida albicans resulting in mouse mortality and morbidity. Carlson E.(PubMed)
(158)Lesson of the month 2: toxic shock syndrome.
Shalaby T1, Anandappa S2, Pocock NJ2, Keough A2, Turner A2.(PubMed)
(159)Staphylococcal toxic shock syndrome: superantigen-mediated enhancement of endotoxin shock and adaptive immune suppression. Kulhankova K1, King J, Salgado-Pabón W.(PubMed)
(160) Toxic Shock Syndrome, C health
(161)Group A streptococcal toxic shock syndrome with extremely aggressive course in the third trimester. Sugiyama T1, Kobayashi T, Nagao K, Hatada T, Wada H, Sagawa N.(PubMed).
(162) Scalded skin syndrome, the university of Maryland medical center
(163)Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study. Kett DH1, Azoulay E, Echeverria PM, Vincent JL; Extended Prevalence of Infection in ICU Study (EPIC II) Group of Investigators.(PubMed)
(164) [Infectious and metabolic nervous system complications of systemic cancer].[Article in Spanish]Ortiz N1.(PubMed)
(165) [Voriconazole compromises renal function in an elderly CDK patient with Candida albicans infection].[Article in Italian] Anastasio P1,.(PubMed)
(166)Endogenous thrombospondin-1 regulates leukocyte recr Marcarelli F, Bilancio G, Mele AA, De Santo NGuitment and activation and accelerates death from systemic candidiasis. Martin-Manso G1, Navarathna DH, Galli S, Soto-Pantoja DR, Kuznetsova SA, Tsokos M, Roberts DD.(PubMed)
(167) [Life-threatening complications of Crohn’s disease and ulcerative colitis: a systematic analysis of admissions to an ICU during 18 years]. [Article in German] Huber W1, Herrmann G, Schuster T, Phillip V, Saugel B, Schultheiss C, Hoellthaler J, Gaa J, Hartel M, Schmid RM, Reindl W.(PubMed)
(168)The role of Candida albicans in the pathogenesis of food-intolerant irritable bowel syndrome. Shepherd C.(PubMed)
(169) Yeasts in the gut: from commensals to infectious agents. Schulze J1, Sonnenborn U.(PubMed)
(170) Treatment of abdominal pain in irritable bowel syndrome. Vanuytsel T1, Tack JF, Boeckxstaens GE.(PubMed)
(171) Current gut-directed therapies for irritable bowel syndrome. Chang HY1, Kelly EC, Lembo AJ.(PubMed)
(172) Abdominal pain in Irritable Bowel Syndrome: a review of putative psychological, neural and neuro-immune mechanisms.Elsenbruch S1.(PubMed)
(173) [Changes of etiology of chronic sinusitis].[Article in Chinese] Deng Q1, Peng P.(PubMed)
(174)Invasive fungal sinusitis of the sphenoid sinus. Lee DH1, Yoon TM1, Lee JK1, Joo YE2, Park KH3, Lim SC1.(PubMed)
(175) Occurrence of killer yeasts in isolates of clinical origin. Robledo-Leal E1, Villarreal-Treviño L, González GM.(PubMed)
(176)Experiences of daily activity in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their implications for rehabilitation programmes. Pemberton S1, Cox DL.(PubMed)
(177) Chronic illness associated with mold and mycotoxins: is naso-sinus fungal biofilm the culprit? Brewer JH1, Thrasher JD, Hooper D.(PubMed)
(178) Detection of mycotoxins in patients with chronic fatigue syndrome.Brewer JH1, Thrasher JD, Straus DC, Madison RA, Hooper D.(PubMed)
(179) Exposure to zearalenone mycotoxin alters in vitro porcine intestinal epithelial cells by differential gene expression.Taranu I1, Braicu C2, Marin DE3, Pistol GC3, Motiu M3, Balacescu L2, Beridan Neagoe I2, Burlacu R4.(PubMed)
(180)Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome.
Forsyth LM1, Preuss HG, MacDowell AL, Chiazze L Jr, Birkmayer GD, Bellanti JA.(PubMed)
(181) Identification of Candida albicans genes induced during thrush offers insight into pathogenesis. Cheng S1, Clancy CJ, Checkley MA, Handfield M, Hillman JD, Progulske-Fox A, Lewin AS, Fidel PL, Nguyen MH.(PubMed)
(182) Is endometrial infection with Candida albicans a cause of recurrent vaginal thrush?Smith JR1, Wells C, Jolly M, Shah P, Savage M, Reginald P, Kitchen VS.(PubMed)
(183) Candida albicans-specific lymphoproliferative and cytokine (IL-4 and IFN-gamma) responses in atopic eczema dermatitis syndrome. Evidence of CD4/CD8 and CD3/CD16+CD56 ratio elevations in vitro. Kosonen J1, Luhtala M, Viander M, Kalimo K, Terho EO, Savolainen J.(PubMed)
(184) Candida albicans mannan- and protein-induced humoral, cellular and cytokine responses in atopic dermatitis patients. Savolainen J1, Kosonen J, Lintu P, Viander M, Pène J, Kalimo K, Terho EO, Bousquet J.(PubMed)
(185) Guidelines for treatment of atopic eczema (atopic dermatitis) Part II.
Ring J1, Alomar A, Bieber T, Deleuran M, Fink-Wagner A, Gelmetti C, Gieler U, Lipozencic J, Luger T, Oranje AP, Schäfer T, Schwennesen T, Seidenari S, Simon D, Ständer S, Stingl G, Szalai S, Szepietowski JC, Taïeb A, Werfel T, Wollenberg A, Darsow U; European Dermatology Forum; European Academy of Dermatology and Venereology; European Task Force on Atopic Dermatitis; European Federation of Allergy; European Society of Pediatric Dermatology; Global Allergy and Asthma European Network.(PubMed)
Posted by kyle J. Norton at 05:00

*****************************************************

http://kylejnorton.blogspot.ca/2015/03/the-holistic-approach-for-prevention_24.html

Tuesday, 24 March 2015
The Holistic approach for Prevention, controlling and Treatment – Chinese Herbs for restore balance of the body after treatment of Candida Albicans Overgrowth

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

What is Candida Albicans
Candida albicans are members of a large group of micro organism whose cells contain complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and mold(6) that live among the gut flora in the human mouth and gastrointestinal tract. In fact, under normal circumstances, Candida albicans that do not cause harmful effects, but overgrowth result in candidiasis. Non-albicans Candida (NAC) species cause 35-65% of all candidaemias in the general patient population(1). According to joint study, in many cases, biofilm(microorganisms with cells stick to each other on a surface) formation(7) gene mutations(8) and overexpression of genes(9)(10) are often associated with increased Candida resistance toward antifungal agents.

Treatment

In Traditional Chinese Medicine

In traditional Chinese medicine, candidiasis is defined as a malfunction of the Triple Burner-related condition due to spleen and stomach disorder(401), causing excess fluid or phlegm in our system(402), weakening immune system(403)(402), leading to damp heat accumulates in the Lower, Middle and Upper Burner causes of candidiasis(401).

Tonifying herbs

After cleansing the body with the above herbs, repairing the damage and restoring the balance are vital to prevent the reoccurring of the pathological factors in TCM.

1. Ren Shen (Radix Ginseng)
Ren shen is aslo best known as Ginseng, a slow-growing plant, belonging to the Panax genus in the family Araliaceae. The smells aromatic, tastes sweet and slightly warm herb(541) has been used in TCM as anti cancer(542)(543), anti aging(544)(545) medicine and to enhance central nervous (546)(547), immune(548)(549), and circulatory system(549)(551) as it tonifies original qi, spleen, lungs and enhances the generation of body fluids by promoting the function of lung and spleen channels(541).
According to China Academy of Chinese Medical Sciences formula ginseng-sanqi extract (GSE) showed to tonify qi and activating blood circulation in promoting endothelial proliferation(an increase in vascular endothelial cells needed for the growth of new or existing blood vessels) and angiogenesis( a process of growing new blood vessels form from pre-existing vessel), through enhancing the expression of angiogenesis signaling proteins (VEGFR-2, Ras, MAPK)(552).

2. Bai Zhu (Rhizoma Atractylodis Macrocephalae)
Bai zhu is also known as Bighead atractylodis rhizome, a genus Atractylodis, belonging to the family Asteraceae. The aromatic, acrid, and sweet herb(553) has been used in TCM as antioxidant(554)(555), to treat liver diseases(556), liver cancer(558)(559), Meniere’s disease(560), intestinal diseases(561), chronic back pain(562), acute infection of intestine(563) as it regulates the functions of liver and spleen, benefiting qi, and nourishing blood(557) by enhancing the functions of spleen and stomach channels(553).

3. Fu Ling (Sclerotium Poriae Cocos)
Fu ling is also known as Poria or china root, is a fungus in the genus Wolfiporia, belonging to family Polyporaceae. The sweet and neutral herb has been used in TCM as inflammatory(566)(567), diuretics(569)(570), anticancer(572)(573), antioxidant(573)(574) and anti-fungal and anti-bacterial(575)(571) agents, and to treat headache(568), cardiovascular diseases(576), neuro disorders(577) insomnia(578), loss of appetite(564) as it strengthens spleen and calms the mind by clearing away the stomach-heat, purging the heart fire, strengthening the spleen and tonifying the kidney(565) through enhancing the function of heart, spleen, lung, kidney channels(564).

4. Chen Pi (Pericarpium Citri Reticulatae)
Chen Pi, also known as Tangerine Peel, is the skin of is an orange-coloured citrus fruit, belonging to the genus Citrus in the family Rutaceae. The bitter, acrid, warm herb has been used in TCM as antioxidant(580)(582), antimicrobial(579)(580)(581) and cytotoxic(580)(583) agents and to improve digestive functions(584), stop bleeding(585), increase blood pressure(585) and stimulate blood vessels(585) as it regulates qi and the middle burner, dry dampness and transform phlegm(586) by promoting the functions of lung and spleen channels(585).

5. Ban Xia (Rhizoma Pinelliae Ternatae)
Ban xia is also known as Pinellia Tuber, a genus of Pinellia, belonging to the family Araceae and native to China. The acrid, warm, toxic herb(587)been used in TCM as anti nephritis(587)(592), anti cancer(589)(590), anti diabetic(591), anti hypercholesterol(592(598)), expectorant(593) and anti convulsant(594) agents and to facilitate gastric disorders(588), get rid of phlegm(597) and induce calming(596) as it dries dampness(587), and tonifies middle burner that aids digestion(595) by enhancing the functions of lung, spleen and stomach channels(587).
According to Nanjing University, banxia also exhibited anti microbial activities, including candida albicans, through its phytochemicial Pinelloside(596). crude extracts of 7 spcies, including sha ren

6. Sha Ren (Adenophora verticillata, Fisch)
Sha Ren is also known as cardamom seeds, the tree is belong to the genus Elettaria and Amomum in the family Zingiberaceae, native to in Asia and Australia. The acrid, warm and nontoxic(599) herb
has been used in TCM to treat digestive tract disorders(600)(601), such as bloating, stomach ache, nausea, vomiting and lack of appetite and gastric ulcer, as it transforms dampness(604), stimulate movement of qi and warms the middle burner(603) by promoting the functions of kidney, spleen and stomach channels(599).
According to University of Medical Sciences, showed effectively 100% inhibition of the pathogen mycelial growth, through it s anti fungal effects(602), in vitro.

7. Mu Xiang (Radix Aucklandiae)
Mu Xiang is also known as costus root, a genus is a genus Saussurea in the family Asteraceae, native to cool temperate helps to and arctic regions of Asia, Europe, and North America. The acrid, bitter and warm herb(605) has been used in TCM as anti microbial(606), anti diabetic(607) and, anti gastric ulcer(611) anti cancer(608)(609) agents and to treat digestive disorders(612), such as pain in the abdomen, diarrhea, vomiting caused by weak digestion, digestive tract infection(606) and yeast infection(606) as it enhances movement of qi, regulates the middle burner(612), dissolves damp-heat(610) by promoting the functions of gallbladder, large intestine, spleen, stomach channels(603).

+ References
(1) Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance by Krcmery V1, Barnes AJ.(PubMed)
(2) Pathogenicity and drug resistance in Candida albicans and other yeast species. A review by Mishra NN1, Prasad T, Sharma N, Payasi A, Prasad R, Gupta DK, Singh R.(PubMed)
(3) Multidrug resistance in yeast Candida by Prasad R1, Kapoor K.(PubMerd)
(4) New evidence that Candida albicans possesses additional ATP-binding cassette MDR-like genes: implications for antifungal azole resistance. by Walsh TJ1, Kasai M, Francesconi A, Landsman D, Chanock SJ.(PubMed)
(5) Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.by Sanglard D1, Kuchler K, Ischer F, Pagani JL, Monod M, Bille J.(PubMed)
(6) Structural analysis of phospho-D-mannan-protein complexes isolated from yeast and mold form cells of Candida albicans NIH A-207 serotype A strain by Shibata N1, Fukasawa S, Kobayashi H, Tojo M, Yonezu T, Ambo A, Ohkubo Y, Suzuki S.(PubMed)
(7) The effect of antifungal combination on transcripts of a subset of drug-resistance genes in clinical isolates of Candida species induced biofilms by Ibrahim NH1, Melake NA2, Somily AM3, Zakaria AS4, Baddour MM5, Mahmoud AZ6(PubMed)
(8) Antifungal drug resistance in pathogenic fungi. by Vanden Bossche H1, Dromer F, Improvisi I, Lozano-Chiu M, Rex JH, Sanglard D.(PubMed)
(9) The genetic basis of fluconazole resistance development in Candida albicans by Morschhäuser J1.(PubMed)
(10) A proteomic approach to understanding the development of multidrug-resistant Candida albicans strains by Kusch H1, Biswas K, Schwanfelder S, Engelmann S, Rogers PD, Hecker M, Morschhäuser J.(PubMed)
(541) Ren shen(Complementary and Alternative Healing University)
(542) Anti-proliferative effect of ginseng saponins on human prostate cancer cell line by Liu WK1, Xu SX, Che CT.(PubMed)
(543) Stereoisomer-Specific Anticancer Activities of Ginsenoside Rg3 and Rh2 in HepG2 Cells: Disparity in Cytotoxicity and Autophagy-Inducing Effects Due to 20(S)-Epimers by Cheong JH1, Kim H, Hong MJ, Yang MH, Kim JW, Yoo H, Yang H, Park JH, Sung SH, Kim HP, Kim J.(PubMed)
(544) Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging by Zhu J1, Mu X1, Zeng J2, Xu C1, Liu J1, Zhang M1, Li C1, Chen J3, Li T3, Wang Y1.(PubMed)
(545) Fermenting red ginseng enhances its safety and efficacy as a novel skin care anti-aging ingredient: in vitro and animal study by Lee HS1, Kim MR, Park Y, Park HJ, Chang UJ, Kim SY, Suh HJ.(PubMed)
(546) Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging by Zhu J1, Mu X1, Zeng J2, Xu C1, Liu J1, Zhang M1, Li C1, Chen J3, Li T3, Wang Y1.(PubMed)
(547) Neuroprotective effect of water extract of Panax ginseng on corticosterone-induced apoptosis in PC12 cells and its underlying molecule mechanisms by Jiang Y1, Li Z1, Liu Y1, Liu X1, Chang Q1, Liao Y1, Pan R2.(PubMed)
(548) Immune system effects of echinacea, ginseng, and astragalus: a review by Block KI1, Mead MN.(PubMed)
(549) Ginseng, the ‘Immunity Boost’: The Effects of Panax ginseng on Immune System by Kang S1, Min H.(PubMed)
(550) A review on the medicinal potentials of ginseng and ginsenosides on cardiovascular diseases by Lee CH1, Kim JH2.(PubMed)
(551) Cardiovascular Diseases and Panax ginseng: A Review on Molecular Mechanisms and Medical Applications by Kim JH1.(PubMed)
(552) [Effect of ginseng-sanqi extract on the Ras associated signal proteins].[Article in Chinese] by Tian W1, Lei Y, Zhu LQ.(PubMed)
(553) Bai zhu(Complementary and Alternative Healing University)
(554) Antioxidant activity of qizhu tang by Wang XJ1, Feng P.(PubMed)
(555) Antioxidant potential of qizhu tang, a chinese herbal medicine, and the effect on cerebral oxidative damage after ischemia reperfusion in rats by Xuejiang W1, Ichikawa H, Konishi T.(PubMed)
(556) Compositions for protecting liver, or for preventing or treating liver fibrosis or cirrhosis US 20080260870 A1
(557) Investigation of the Chemical Changes from Crude and Processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma Herbal Pair Extracts by Using Q Exactive High-Performance Benchtop Quadrupole-Orbitrap LC-MS/MS by Cao G1, Li Q2, Cai H3, Tu S4, Cai B1.(PubMed)
(558) Atractylenolide II induces G1 cell-cycle arrest and apoptosis in B16 melanoma cells byYe Y1, Wang H, Chu JH, Chou GX, Chen SB, Mo H, Fong WF, Yu ZL.(PubMed)
(559) Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits by Ma L1, Mao R1, Shen K1, Zheng Y1, Li Y1, Liu J2, Ni L3.(PubMed)
(560) The Treatment of Modern Western Medical Diseases with Chinese Medicine: A … By Bob Flaws, Philippe Sionneau, page 364
(561) Literature-based analysis on relationship of symptoms, drugs and therapies in treatment of intestinal diseases by Gao L, Wang J, Li F, Deng Y, Gao S.(PubMed)
(562) The Treatment of Modern Western Medical Diseases with Chinese Medicine: A … By Bob Flaws, Philippe Sionneau, page 346
(563) Fermented Rhizoma Atractylodis Macrocephalae alleviates high fat diet-induced obesity in association with regulation of intestinal permeability and microbiota in rats by Wang JH1, Bose S2, Kim HG3, Han KS3, Kim H3.(PubMed)
(564) Fu ling(Complementary and Alternative Healing University)
(565) Treatment of incipient diabetic nephropathy by clearing away the stomach-heat, purging the heart fire, strengthening the spleen and tonifying the kidney by Wu S1, Han Y, Li J.(PubMed)
(566) Ethanol extract of Poria cocos reduces the production of inflammatory mediators by suppressing the NF-kappaB signaling pathway in lipopolysaccharide-stimulated RAW 264.7 macrophages by Jeong JW, Lee HH, Han MH, Kim GY, Hong SH, Park C, Choi YH1.(PubMed)
(567) Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions by Prieto JM1, Recio MC, Giner RM, Máñez S, Giner-Larza EM, Ríos JL.(PubMed)
(568) [Syndrome differentiation and treatment of Taiyang disease in Shanghan Lun].[Article in Chinese] by Yang X1, Peng WB, Yue XQ.(PubMed)
(569) Diuretic activity of some fractions of the epidermis of Poria cocos by Feng YL1, Lei P, Tian T, Yin L, Chen DQ, Chen H, Mei Q, Zhao YY, Lin RC.(PubMed)
(570) Diuretic activity of the ethanol and aqueous extracts of the surface layer of Poria cocos in rat by Zhao YY1, Feng YL, Du X, Xi ZH, Cheng XL, Wei F.(PubMed)
(571) Biological activities and potential health benefits of polysaccharides from Poria cocos and their derivatives by Sun Y1.(PubMed)
(572) Triterpenes from Poria cocos suppress growth and invasiveness of pancreatic cancer cells through the downregulation of MMP-7 by Cheng S1, Eliaz I, Lin J, Thyagarajan-Sahu A, Sliva D.(PubMed)
(573) Cytotoxic and anti-oxidant activities of lanostane-type triterpenes isolated from Poria cocos by Zhou L1, Zhang Y, Gapter LA, Ling H, Agarwal R, Ng KY.(PubMed)
(574) Antioxidant activity of carboxymethyl (1→3)-β-d-glucan (from the sclerotium of Poria cocos) sulfate (in vitro) by Wang Q1, Chen S2, Han L2, Lian M2, Wen Z2, Jiayinaguli T2, Liu L2, Sun R2, Cao Y3.(PubMed)
(575) Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs by Zhang L1, Ravipati AS, Koyyalamudi SR, Jeong SC, Reddy N, Bartlett J, Smith PT, de la Cruz M, Monteiro MC, Melguizo A, Jiménez E, Vicente F.(PubMed)
(576) Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential. by Wong KL1, Wong RN2, Zhang L1, Liu WK3, Ng TB3, Shaw PC4, Kwok PC5, Lai YM6, Zhang ZJ1, Zhang Y1, Tong Y1, Cheung HP1, Lu J1, Sze SC1.(PubMed)
(577) A activitiesUse of Yokukansan (TJ-54) in the treatment of neurological disorders: a review by de Caires S1, Steenkamp V.(PubMed)
(578) Over-the-counter sleeping pills: a survey of use in Hong Kong and a review of their constituents by Chung KF1, Lee CK.(PubMed)
(579) Antimicrobial activity of acid-hydrolyzed Citrus unshiu peel extract in milk by Min KY1, Kim HJ2, Lee KA1, Kim KT3, Paik HD4.(PubMed)
(580) New depside from Citrus reticulata Blanco by Phetkul U1, Phongpaichit S, Watanapokasin R, Mahabusarakam W(PubMed)
(581) Anti-fungal activity of Citrus reticulata Blanco essential oil against Penicillium italicum and Penicillium digitatum by Tao N1, Jia L2, Zhou H2.(PubMed)
(582) Phenolic compositions and antioxidant capacities of Chinese wild mandarin (Citrus reticulata Blanco) fruits by Zhang Y1, Sun Y, Xi W, Shen Y, Qiao L, Zhong L, Ye X, Zhou Z.(PubMed)
(583) Differential inhibition of human cancer cell proliferation by citrus limonoids by Tian Q1, Miller EG, Ahmad H, Tang L, Patil BS.(PubMed)
(584) EFFICACY OF CITRUS FRUIT PEEL EXTRACTS AGAINST PATHOGENS CAUSING GASTROINTESTINAL DISORDERS SRIVIDHYA. M1,2, RAMANATHAN. K2 AND KRISHNANAND. N.(International Journal of Pharmacy and Pharmaceutical Sciences)
(585) Chen pi(Complementary and Alternative Healing University)
(586) Encyclopedic Reference of Traditional Chinese Medicine edited by Yang Xinrong, page 542
(587) Ban xia(Complementary and Alternative Healing University)
(588) Effect of Pinellia ternata tuber on the efferent activity of the gastric vagus nerve in the rat.
Niijima A1, Okui Y, Kubo M, Higuchi M, Taguchi H, Mitsuhashi H, Maruno M.(PubMed)
(589) Chinese medicine formula “Weikang Keli” induces autophagic cell death on human gastric cancer cell line SGC-7901 by Huo J1, Qin F, Cai X, Ju J, Hu C, Wang Z, Lu W, Wang X, Cao P.(PubMed)
(590) [Effects of ethanol extract of Rhizome Pinelliae Preparata on intracellular pH value of human gastric adenocarcinoma cells].[Article in Chinese]by Zhang CA1, Wu F, Mao ZJ, Wei Z, Li YJ, Wei PK.(PubMed)
(591) Anti-diabetic effect of Wen-pi-tang-Hab-Wu-ling-san extract in streptozotocin-induced diabetic rats by Hyo Won Jung, Jin Ki Jung,1 Mahesh Ramalingam, Cheol-Ho Yoon,2 Hyo Sang Bae,2 and Yong-Ki Park (PubMed)
(592) Effects of chai ling tang on proteinuria in rat models by Li P1, Fujio S.(PubMed)
(593) [Effect of jinshui-liujun decoction on chronic bronchitis in rats].[Article in Chinese] by Shen Y1, Lü X, Jiang J, Guo S, Zhao C, Meng H, Li S, Hu X(PubMed)
(594) Sedative, hypnotic and anticonvulsant activities of the ethanol fraction from Rhizoma Pinelliae Praeparatum by Xiang-yang Wu, Jiang-li Zhao, Min Zhang, Fang Li, Ting Zhao, Liu-qing Yang [accessed Mar 22, 2015](Researchgate)
(595) 2008 VOLUME 3 ISSUE 1Australian Journalof Acupuncture and Chinese Medicine25Modern Applications ofModifiedBan Xia Xie Xin Tangand Their Development by Hong Xu, PhD and Wen Xuan Zhang, PhD
(596) Pinelloside, an antimicrobial cerebroside from Pinellia ternata byChen JH1, Cui GY, Liu JY, Tan RX.(PubMed)
(597) [Optimized treatment program for unstable angina by integrative medicine based on partially observable Markov decision process].[Article in Chinese]by Feng Y1, Xu H, Liu K, Zhou XZ, Chen KJ.(PubMed)
(598) Anti-obesity effect of Pinellia ternata extract in Zucker rats by Kim YJ1, Shin YO, Ha YW, Lee S, Oh JK, Kim YS.(PubMed)
(599) Sha ren(Complementary and Alternative Healing University)
(600) Gastroprotective effect of cardamom, Elettaria cardamomum Maton. fruits in rats by Jamal A1, Javed K, Aslam M, Jafri MA.(PubMed)
(601) Evaluation of the gastric antiulcerogenic effect of large cardamom (fruits of Amomum subulatum Roxb). by Jafri MA1, Farah, Javed K, Singh S.(PubMed)
(602) Anti-fungal activity of cold and hot water extracts of spices against fungal pathogens of Roselle (Hibiscus sabdariffa) in vitro by Touba EP1, Zakaria M, Tahereh E.(PubMed)
(603) Herbal Formulas II Dr. Li, Dongcheng
(604) Foundations for Integrative Musculoskeletal Medicine: An East-west Approach By Alon Marcus, page 104
(605) Mu xiang(Complementary and Alternative Healing University)
(606) Antibiotic principle of Eupatorium capillifolium by Rao KV, Alvarez FM.(PubMed)
(607)Normo-glycemic and hypolipidemic effect of costunolide isolated from Costus speciosus (Koen ex. Retz.)Sm. in streptozotocin-induced diabetic rats by Eliza J1, Daisy P, Ignacimuthu S, Duraipandiyan V.(PubMed)
(608) [Effect of costus root oil in murine tumors].[Article in Japanese] by Takanami I, Ikeda Y, Nakayama H.(PubMed)
(609) [Cutaneous delayed hypersensitivity to costus root oil in lung cancer].[Article in Japanese] by Takanami I, Ishihara T, Yanai N(PubMed)
(610) [Observation of the curative effect of qingchang huashi recipe for treating active ulcerative colitis of inner-accumulation of damp-heat syndrome].[Article in Chinese] by He HH1, Shen H, Zheng K.(PubMed)
(611) [Study of the effect of exceed critical extracts from Radix Aucklandiae on experimental gastric ulcer model].[Article in Chinese] by Han J1, Lin H, Zhong Z, Rong X.(PubMed)
(612) Authentication of Radix Aucklandiae and its substitutes by GC-MS and hierarchical clustering analysis by Shum KC1, Chen F, Li SL, Wang J, But PP, Shaw PC.(PubMed)
(613) Radix Aucklandiae, TCM Wiki
Posted by kyle J. Norton at 04:18

Advertisements


Leave a comment

The Holistic approach for Prevention, controlling and Treatment of Candida Albicans Overgrowth – Healing the intestinal membrane

http://kylejnorton.blogspot.com/2015/03/the-holistic-approach-for-prevention_18.html

Wednesday, 18 March 2015
The Holistic approach for Prevention, controlling and Treatment of Candida Albicans Overgrowth – Healing the intestinal membrane

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

What is Candida Albicans
Candida albicans are members of a large group of micro organism whose cells contain complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and mold(6) that live among the gut flora in the human mouth and gastrointestinal tract. In fact, under normal circumstances, Candida albicans that does not cause harmful effects, but overgrowth results in candidiasis. Non-albicans Candida (NAC) species cause 35-65% of all candidaemias in the general patient population(1). According to joint study, in many cases, biofilm(microorganisms with cells stick to each other on a surface) formation(7) gene mutations(8) and overexpression of genes(9)(10) are often associated with increased Candida resistance toward antifungal agents.

Treatments and controllings

Healing the intestinal membrane
1. L-glutamine
L-glutamine is one of the 20 amino acids encoded by the standard genetic code and used to treat certain gastrointestinal disorders(342)(343) by serving as a source of fuel for the cells that line the gastrointestinal tract. According to Ankara University, L-glutamine inhibited the over growth of candida through its antimutagenic and antimicrobial activities(344).

2. N-acetyl-glucosamine
N-acetyl-glucosamine is a monosaccharide derivative of glucose that supports the digestive track function and maintains healthy intestinal lining by stimulating cell growth in the intestinal track(345). According to 1National Institute of Plant Genome Research, GIG2 (GlcNAc-induced gene 2). involved in the metabolism of N-acetylneuraminate (sialic acid), effectively decrease in fungal burden in mouse model(346).

3. Rice-bran oil
Rice-bran oil, extracted from the germ and inner husk of rice, containing a compound gamma-oryzanol(347) showed to reduce the risk of gastric ulcers caused by stress while at the same time maintaining gastrointestinal motility(348). According to Manipal Academy of Higher Education (Deemed University, rice bran oil immobilized lipase from Candida, a potential pathway for fungal overgrowth(349).

4. Pancreatic enzymes products
Pancreatic enzymes allow for more bacteria to grow in the intestine enabling the food to be digested a lot easier(350). it can be found as supplements and in certain foods. Insufficient pancreatic enzymes can quickly encourage Candida overgrowth the digestive tracts(351).

5. Butyric acid
Butyric acid, a fatty acid occurring in the form of esters in animal fats and plant oils, has found to be effective in inhibited pathogenic organisms(352), improved digestion and promoted intestinal health(353) by producing bacteria to feed on lactic acid, then multiplying and revving up their production(354) . Butyric acid also consists anti-inflammatory property(355) and strengthens the intestinal mucosal barrier.(356).

5. Fructo-oligosaccharides(FOS)
Fructo-oligosaccharides(FOS) is a class of oligosaccharides used as an artificial or alternative sweetener(357), extracted from fruits and vegetables such as bananas, onions, chicory root, garlic, asparagus, barley, wheat, tomatoes, and leeks(358). It is inulin-type prebiotics(359), stimulated the growth of friendly bacteria in the intestine track to counter react to other bad bacteria(360)(362) such as candida but it may cause gas formation, through increasing faecal biomass and water content of the stools, for improvement of bowel habits(361)

6. Etc.

+ References
(1) Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance by Krcmery V1, Barnes AJ.(PubMed)
(2) Pathogenicity and drug resistance in Candida albicans and other yeast species. A review by Mishra NN1, Prasad T, Sharma N, Payasi A, Prasad R, Gupta DK, Singh R.(PubMed)
(3) Multidrug resistance in yeast Candida by Prasad R1, Kapoor K.(PubMerd)
(4) New evidence that Candida albicans possesses additional ATP-binding cassette MDR-like genes: implications for antifungal azole resistance. by Walsh TJ1, Kasai M, Francesconi A, Landsman D, Chanock SJ.(PubMed)
(5) Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.by Sanglard D1, Kuchler K, Ischer F, Pagani JL, Monod M, Bille J.(PubMed)
(6) Structural analysis of phospho-D-mannan-protein complexes isolated from yeast and mold form cells of Candida albicans NIH A-207 serotype A strain by Shibata N1, Fukasawa S, Kobayashi H, Tojo M, Yonezu T, Ambo A, Ohkubo Y, Suzuki S.(PubMed)
(7) The effect of antifungal combination on transcripts of a subset of drug-resistance genes in clinical isolates of Candida species induced biofilms by Ibrahim NH1, Melake NA2, Somily AM3, Zakaria AS4, Baddour MM5, Mahmoud AZ6(PubMed)
(8) Antifungal drug resistance in pathogenic fungi. by Vanden Bossche H1, Dromer F, Improvisi I, Lozano-Chiu M, Rex JH, Sanglard D.(PubMed)
(9) The genetic basis of fluconazole resistance development in Candida albicans by Morschhäuser J1.(PubMed)
(10) A proteomic approach to understanding the development of multidrug-resistant Candida albicans strains by Kusch H1, Biswas K, Schwanfelder S, Engelmann S, Rogers PD, Hecker M, Morschhäuser J.(PubMed)
(342) Glutamine supplementation for young infants with severe gastrointestinal disease. by Brown JV1, Moe-Byrne T, McGuire W.(PubMed)
(343) Glutamine and intestinal barrier function ,By Wang B1, Wu G, Zhou Z, Dai Z, Sun Y, Ji Y, Li W, Wang W, Liu C, Han F, Wu Z.(PubMed)
(344) Schiff bases attached L-glutamine and L-asparagine: first investigation on antimutagenic and antimicrobial analyses by Sakiyan I1, Anar M, Oğütcü H, Agar G, Sarı N.(PubMed)
(345)Explore The Truth On Cures For Yeast Infection(Thing for Ladies)
(346) and maintains healthy intestinal lining(Thing for Ladies)
(347) Role of gamma-oryzanol in drought-tolerant and susceptible cultivars of rice (Oryza sativa L.) by Kumar MS, Dahuja A, Rai RD, Walia S, Tyagi A.(PubMed)
(348) [Effects of gamma-oryzanol on gastric lesions and small intestinal propulsive activity in mice].
[Article in Japanese] by Ichimaru Y, Moriyama M, Ichimaru M, Gomita Y.(PubMed)
(349) Hydrolysis of rice bran oil using an immobilized lipase from Candida rugosa in isooctane by Murty VR1, Bhat J, Muniswaran PK.(PubMed)
(350) The use of dual-isotope imaging to compare the gastrointestinal transit of food and pancreatic enzyme pellets in cystic fibrosis patients by Hillel PG1, Tindale WB, Taylor CJ, Frier M, Senior S, Ghosal S.(PubMed)
(351) The Best Digestive Enzymes For Candida(Digestive health Guide)
(352) Purification and characterization of antibacterial substances produced by a marine bacterium Pseudoalteromonas haloplanktis strain by Hayashida-Soiza G1, Uchida A, Mori N, Kuwahara Y, Ishida Y.(PubMed)
(353) Induction of rhythmic transient depolarizations associated with waxing and waning of slow wave activity in intestinal smooth muscle by Pawelka AJ1, Huizinga JD2.(PubMed)
(354) Fermentation Analysis & Evaluation(daily one)
(355) Anti-inflammatory effects of sodium butyrate on human monocytes: potent inhibition of IL-12 and up-regulation of IL-10 production by Säemann MD1, Böhmig GA, Osterreicher CH, Burtscher H, Parolini O, Diakos C, Stöckl J, Hörl WH, Zlabinger GJ.(PubMed)
(356) Inhibition of p38 mitogen-activated protein kinase attenuates butyrate-induced intestinal barrier impairment in a Caco-2 cell monolayer model by Huang XZ1, Li ZR, Zhu LB, Huang HY, Hou LL, Lin J.(PubMed)
(357) Functional characterization of sucrose phosphorylase and scrR, a regulator of sucrose metabolism in Lactobacillus reuteri by Teixeira JS1, Abdi R, Su MS, Schwab C, Gänzle MG.(PubMed)
(358) Fructo-oligosaccharides(FOS)(Wikipedia)

(359) [Synthesis of novel fructo-oligosaccharides (FOS) by enzymatic reaction].[Article in French]by Grizard D1, Barthomeuf C.(PubMed)
(360) Inulin-type prebiotics–a review: part 1 by Kelly G.(PubMed)
(361) Introducing inulin-type fructans by Roberfroid MB1.(PubMed)
(362) Studies with Inulin-Type Fructans on Intestinal Infections, Permeability, and Inflammation,
by Francisco Guarner(The Journal of Nutrition)


Leave a comment

Hair Loss – The Causes

http://kylejnorton.blogspot.ca/2013/11/hair-loss-causes.html

Hair Loss – The Causes

The adult scalp contains about 100,000 hair follicles. Everyday the scalp loses about 100 hairs and they will grow back in 5-6 weeks. Starting at age 40, the levels of by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosterones DHT causing our hair to grow back thinner or not grown back at all. This causes an androgenic alopecia hair loss problem, since DHT shrinks the follicles causing hair thins and hair receding at the forehead, crown and temple for men and thins over the entire scalp for women. Aging and other problems causing hair loss will be discussed in this article.

1. Aging
Human aging is the biological process that is unavoidable but controllable with healthy diet with complex carbohydrates, green foods, garlic, onion, water and juices that will help to decrease the aging process in some degree. It also helps to reduce the amount of DHT produced in our body, result in postponing hair loss to our scalp.

2. Mineral deficiency
Minerals such as calcium, iron, copper, chromium, iodine, zinc, and magnesium are necessary to maintain healthy hair growth. Mineral deficiency will reduce the chance to regulate the blood circulation that promotes healthy hair growth and thyroid hormones that prevent dry hair and hair loss as well as defects in hair color. Too much iron is toxic to your body. Be sure to talk to your doctor before taking any mineral supplement.

3. Oxygen deficiency
Oxygen deficiency in your blood weakens the hair follicles, leading to dryness of the scalp and hair loss. Uncontrolled diet that is high in saturated fat causes cholesterol building up in your arteries resulting in less oxygen in your blood stream. Also cigarette smoking and second hand smoke reduces the blood flow and increases the blood clotting activity of cells which would clog the blood flow and damage arteries causing oxygen deficiency and results in weaken of the hair follicles.

4. Side affects of medication taken
Some medications contains elements that might cause hair loss such as lithium, warfarin, heparin, and amphetamines. When hair loss is a side effect of a medication, hair growth usually returns to normal once the drug is stopped.

5. Genetic hair loss Hair loss is due to heredity. It is passed down from generation to generation. Genetic hair loss appears predominately in men, but may also appear in a few select women.

Hair Loss No More
HOW TO STOP YOUR HAIR LOSS NOW!! And 
Strengthen, Restore And Revitalize Thinning Hair Naturally

Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve 
Optimal Health And Loose Weight

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to Women Health http://kylejnorton.blogspot.ca/p/women-health.html
Back to Kyle J. Norton Home Page http://kylejnorton.blogspot.ca


Leave a comment

Anise

http://kylejnorton.blogspot.ca/2013/11/popular-herbs-anise.html

Popular #Herbs – Anise

A. Anise is a flowering plant ofthe species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to to Egypt and the Mediterranean region. The popular herb has been used in traditional herbal medicine as fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic, carminative, digestive, expectorant, stimulant and tonic agent to treat head-lice and mites, increase blood pressure, prevent formation of gas in the gastrointestinal tract and menstrual cramps, etc.

B. Health benefits

1. Anise and Menstrual Cramps and pain
Anise contains certain chemical compounds in relieving the cramps and pain of primary dysmenorrhea, due to immature of the reproductive organs of young girls, according to the study of “The effect of an Iranian herbal drug on primary dysmenorrhea: a clinical controlled trial” by Nahid K, Fariborz M, Ataolah G, Solokian S., posted in PubMed (1), researchers found that The magnitude of the reduction was significantly greater in the SCA (500 mg of highly purified saffron, celery seed, and anise) group than in the mefenamic acid and placebo groups. Both drugs effectively relieved menstrual pain as compared with the placebo. More clinical trials are needed to establish the efficacy of this herbal drug.

2. Thrombosis
Thrombosis is defined as a condition of formation of a blood clot inside a blood vessel, leading to the obstruction of blood flow of the circulatory system. Anrise can help to reduce the risk of thrombosis due to the essential oil anethole, according to the study of “Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis” by Tognolini M, Ballabeni V, Bertoni S, Bruni R, Impicciatore M, Barocelli E., posted in PubMed (2), researchers found that both F. vulgare essential oil and anethole (100 mg kg(-1) oral administration) provided significant protection toward ethanol induced gastric lesions in rats. In conclusion, these results demonstrate for F. vulgare essential oil, and its main component anethole, a safe antithrombotic activity that seems due to their broad spectrum antiplatelet activity, clot destabilizing effect and vasorelaxant action.

3. Head louse infestation

Eventhough Permethrin has been used most widely as an insecticide, acaricide, and insect repellent to treat Head louse infestation, but as a result of mutation of the fests which makes the Permethrin less effective, anise is considered as one of replacement for the synthetic chemical, according to the study of “Clinical trial showing superiority of a coconut and anise spray over permethrin 0.43% lotion for head louse infestation, ISRCTN96469780.” by Burgess IF, Brunton ER, Burgess NA., posted in PubMed(3)

4. Herpes simplex virus
Anise oil, in some studies has demonstrated the exhibition of the high levels of antiviral activity against HSV, according to the study of “Efficacy of anise oil, dwarf-pine oil and chamomile oil against thymidine-kinase-positive and thymidine-kinase-negative herpesviruses” by Koch C, Reichling J, Kehm R, Sharaf MM, Zentgraf H, Schneele J, Schnitzler P., posted in pubMed(4)

5. Tongue squamous carcinoma

The ingredient of anise, Safrole has shown a property of induced apoptosis in human tongue squamous cancer SCC-4 cells, as aresult od involvment in mitochondria- and caspase-dependent signal pathwaysaccording to the study of “Safrole induces cell death in human tongue squamous cancer SCC-4 cells through mitochondria-dependent caspase activation cascade apoptotic signaling pathways” by Yu FS, Huang AC, Yang JS, Yu CS, Lu CC, Chiang JH, Chiu CF, Chung JG., posted in PubMed(5).

6. Antiviral activity

Extract of anise have shown an antiviral property of inhibition of the spread of the infectous virus, such as virus types 1 and 2 (HSV-1 and -2), human cytomegalovirus (HCMV) and measles virus by interfering the virus adsorption to the host cell surface, according to the study of “Antiviral and immunostimulating effects of lignin-carbohydrate-protein complexes from Pimpinella anisum” by Lee JB, Yamagishi C, Hayashi K, Hayashi T., posted in PubMed(6)

7. antioxidant and anti-fungal activities

Anethole, the ingredient in anise has shown the property of antioxidant and antifungal activities that can lead to the use as natural preservatives for food products. according to the study of “Chemistry, antioxidant, antibacterial and antifungal activities of volatile oils and their components” by De Martino L, De Feo V, Fratianni F, Nazzaro F., posted in PubMed(7)

8. Candida

The chemicals compound of Anise, anisaldehyde has shown a property in inhibition of fungal activity on patient with Candida,including azole-resistant strains, according to the study of “Interesting anticandidal effects of anisic aldehydes on growth and proton-pumping-ATPase-targeted activity’ by Shreaz S, Bhatia R, Khan N, Ahmad SI, Muralidhar S, Basir SF, Manzoor N, Khan LA., posted in PubMed(8)

9. Hypnotic and anticonvulsant
Acetophenone, a ingredient of Anise was used in medicine in the late and early 20 century under the drug named Hypnone and considered as a representative analgesic and hypnotic used to treat painful affections of the fifth nerve, tic-douloureux, rheumatic disturbances of the dental branches of the same nerve, in hemicrania, and similar disorders, etc., according to the article of
“Hypnone”, posted in Chest of Books.com(9)

10. Gastroesophageal reflux disease and heartburn
Limonene, another ingredient of Anise has been used in treating Gastroesophageal reflux disease and heartburn, as aresult of its its gastric acid neutralizing effect and its support of normal peristalsis, according to the study of “D-Limonene: safety and clinical applications” by Sun J., posted in PubMed(10)

11. Water retention
It is said the Anise can help to increase urine excretion and reduce the risk of water retention and floating, according to the article of “Water Retention Remedies From Your Kitchen” by Janet Martin, posted in Article Base(11)

12. Etc.

C. Side Effects
1. If you have high blood pressure or pregnant please consult with your doctore or related field specialist before applying
2. Star Anise is toxic, according to the study of “[Apparent life-threatening event in infants: think about star anise intoxication!].[Article in French]by Perret C, Tabin R, Marcoz JP, Llor J, Cheseaux JJ., posted in PubMed(12).
3. Skin Irritation
4. Allergic reaction such as mouth and lip inflammation, according to the study of `Aniseed-induced nocturnal tongue angioedema` by Gázquez García V, Gaig Jané P, Bartolomé Zavala B., posted in PubMed(13)
5. Etc.

Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve 
Optimal Health And Loose Weight

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to Popular Chinese Herbs  http://kylejnorton.blogspot.ca/p/chinese-herbs.html
 
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources

(5) http://www.ncbi.nlm.nih.gov/pubmed/21591240
(6) http://www.ncbi.nlm.nih.gov/pubmed/21389629
(7) http://www.ncbi.nlm.nih.gov/pubmed/20120118
(8) http://www.ncbi.nlm.nih.gov/pubmed/21669279
(9) http://chestofbooks.com/health/materia-medica-drugs/Roberts-Bartholow/Practical-Treatise/Hypnone.html
(10) http://www.ncbi.nlm.nih.gov/pubmed/18072821
(11) http://www.ncbi.nlm.nih.gov/pubmed/21652187
(12) http://www.articlesbase.com/diseases-and-conditions-articles/water-retention-remedies-from-your-kitchen-579643.html
13. http://www.ncbi.nlm.nih.gov/pubmed/18088024


Leave a comment

Upper respiratory tract infection – The Diet

http://kylejnorton.blogspot.ca/2013/11/upper-respiratory-tract-infection-diet.html

Upper respiratory tract infection – The Diet

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and  muscles breathing , etc,.
V. A. Upper respiratory tract infection
Upper respiratory tract infections are considered to be the infection of the airway above the glottis or vocal cords. This includes the nose, sinuses, pharynx, and larynx, including the infection of tonsillitis, pharyngitis, laryngitis, sinusitis, otitis media, etc,.
E. Preventions
E.2. Diet to prevent upper respiratory track infection
1. Green tea
In a randomized, double-blind, placebo-controlled trial of 200 healthcare workers conducted for 5 months from November 9, 2009 to April 8, 2010 in three healthcare facilities for the elderly in Higashimurayama, Japan, found that among healthcare workers for the elderly, taking green tea catechins and theanine may be effective prophylaxis for influenza infection(23).
2. Soy
The necessity of introduction soya-based food in a complex treatment of this infection as it enhances processes of detoxication, positevely influences on functional and structural state of the liver, reduces cytolysis, cholestasis symptomes, mesenchymal and inflamation reactions thus increases the tolerance of antimicobacterial agents, according to the study by leaded by Dr. Mel’nyk VP(24).
3. Garlic
In the study of a total of one hundred forty-six volunteers were randomized to receive a placebo or an allicin-containing garlic supplement, one capsule daily, over a 12-week period between November and February, showed that volunteers in the active group were less likely to get a cold and recovered faster if infected. Volunteers taking placebo were much more likely to get more than one cold over the treatment period. An allicin-containing supplement can prevent attack by the common cold virus(25).
4. Etc.
Chinese Secrets To F


Leave a comment

Vertigo – The Do’s and Do not’s list

http://kylejnorton.blogspot.ca/2013/11/vertigo-dos-and-do-nots-list.html

Saturday, 30 November 2013

Vertigo – The Do’s and Do not’s list

Vertigo is defined as a condition of dizziness of feeling of spinning, or swaying when one is stationary. Dizziness is a general, non-specific term to indicate a sense of disorientation. Some researchers suggested that vertigo is a subtype of dizziness and refers to an erroneous perception of self- or object-motion or an unpleasant distortion of static gravitational orientation that is a result of a mismatch between vestibular, visual, and somatosensory systems, affecting approximately 20-30% of the general population(1) and about two to three times higher in women than in men.
Preventions
A. The Do’s and Do not’s list 
1. Unhealthy diet
Unhealthy diet with high in saturated and trans fat and less fruits and vegetables can increase the risk of cholesterol building up in the arteries and nutrients deficiency of that can lead to insufficient blood flow to the back of the brain.

2.  Avoid damage to the head
From a neurotologic perspective, approximately 21.9% of head injured workers were determined to have recognizable evidence of cochleovestibular dysfunction. Olfactory dysfunction as a physical finding post-head injury compares favourably with the presence of post-traumatic benign positional paroxysmal vertigo (BPPV) and its atypical variants in 11.2% of head injured workers(17)

3. Relaxation
In the study of VERTIGO AND PSYCHOLOGICAL DISTURBANCES  Timothy C. Hain, MD, showed that Psychological abnormalities are common in the general population, even more common in those who are ill, and are certainly also common in individuals with vertigo. In a recent study by Garcia et al in Portugal, out of 43 patients, a large number of psychological abnormalities were diagnosed by the SCL-90 (a standard psychological test) including
a. Somatization     41.9%
b. Hostility     20.9%
c. Interpersonal sensitivity     18.6%
d. Anxiety     23.3%
e. Phobic anxiety     20.9%
f. OCD (obsessive compulsive disorder)     53.5%
g. Depression     30.2%
h. Paranoid traits     11.6%
i. Psychotic traits     2.3%(18)

4. Fruits and vegetables
Fruits and vegetables contain high amount of antioxidants and overprotective nutrients of which can enhance the immune system in fighting against firming of free radicals causes of degenerative diseases and viral and bacteria causes of infection and inflammation and decrease the chronic diseases causes of vertigo.

5. Moderate exercise
Excessive exercise can decrease the immune function in fighting against disease, moderate exercise not only enhances the blood circulation to increase oxygen to the back of the brain but also promotes the immune function fighting against inflammation and weaken immune system causes of vertigo.

6. Smoking
Smoking can reduce the lung function in oxygen absorption, thus reducing the risk of oxygen deficiency causes of vertigo.

7. Excessive alcohol drinking
Alcoholism can weaken the immune system and increase the risk of inflammatory causes of vertigo.

8. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve 
Optimal Health And Loose Weight

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca  
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22377855
(17) http://www.ncbi.nlm.nih.gov/pubmed/10445080
(18) http://www.dizziness-and-balance.com/disorders/psych/psych.htm 


Leave a comment

Vertigo

http://kylejnorton.blogspot.com/2013/11/vertigo_3.html

Vertigo

I. Vertigo is defined as a condition of dizziness of feeling of spinning, or swaying when one is stationary. Dizziness is a general, non-specific term to indicate a sense of disorientation. Some researchers suggested that vertigois a subtype of dizziness and refers to an erroneous perception of self- or object-motion or an unpleasant distortion of static gravitational orientation that is a result of a mismatch between vestibular, visual, and somatosensory systems, affecting approximately 20-30% of the general population(1) and about two to three times higher in women than in men.

II. Symptoms
A. Eidelman D. in the study of “Fatigue on rest” and associated symptoms(headache, vertigo, blurred vision, nausea, tension and irritability) due to locally asymptomatic, unerupted, impacted teeth” showed that
1. “Fatigue on Rest“,
2. headache,  
3. vertigo and the feeling of loss of balance,
4. blurred vision,
5. nausea,
6. tension and
7.  irritability
were found to be prevalent amongst patients who had  locally asymptomatic, unerupted impacted teeth. A comparative pressure sign was developed, which, when positive, confirmed the relationship between the impacted teeth and the medical symptoms. Removal of the impactions resulted in the alleviation of the symptoms. Stress and psychogenic factors are considered as trigger mechanisms, rather than as basic causes of the symptoms(2).

B. Other symptoms
Other researchers indicated that Destructive lesions of labyrinth, or of vestibular tracks, partial or complete.-Heterogeneous stimulations of the paired intact vestibular-end organs.-The hypersensitive labyrinth.-Clinical manifestations of vertigo, associated with nausea, headache, 
8. visual disturbances,
9. nystagmus, 
10. diplopia, 
11. staggering gait,
12. vasomotor and cardio-vascular symptoms, 
13. pallor, flushing,  
14. sweating
15. dyspnoea, 
16. fainting, 
17. vomiting and 
18. diarrhoea.
19. Etc.(3)

III. Causes and Risk Factors
 A. Causes
1. DR. Karatas M. at the Baskent University, Medical School, Adana Research Center in a study of Central vertigo and dizziness: epidemiology, differential diagnosis, and common causes indicated that central causes are responsible for almost one-fourth of the dizziness experience by patients. The patient’s history, neurologic examination, and imaging studies are usually the key to differentiation of peripheral and central causes of vertigo. The most common central causes of dizziness and vertigo are  
a. cerebrovascular disorders related to the vertebrobasilar circulation,  
b. migraine, 
c. multiple sclerosis, 
d. tumors of the posterior fossa, 
e. neurodegenerative disorders, 
f.  some drugs, and 
g. psychiatric disorders.(4)

2. Stroke
Stroke accounts for 3-7% among all causes of vertigo. The blood perfusion to the inner ear, brainstem, and cerebellum arise from the vertebrobasilar system. Vertigo, nausea, and vomiting, along with nystagmus, representsymptoms of stroke in posterior fossa due to arterial occlusion or rupture of the vertebrobasilar system. However, the spectrum of signs and symptomsas a manifestation of stroke associated with dizziness and vertigo may be variable depending on the affected vascular territories(1)

3. Meniere’s disease
Meniere’s disease is a clinical syndrome characterized by spontaneous episodes of recurrent vertigo, sensorineural hearing loss, tinnitus and aural fullness and familial Meniere’s disease in around 10-20% of cases. An international collaborative effort to define the clinical phenotype and recruiting patients with migrainous vertigo and Meniere’s disease is ongoing for genome-wide association studies(5).

4. Diabetes
Some researchers at the GENyO Pfizer-Universidad de Granada suggested that suggest that type 1 diabetes mellitus is associated with cupular and free-floating deposits in the semicircular canals. The patients with type 1 diabetes mellitus with a longer duration of disease have an increased probability of suffering from benign paroxysmal positional vertigo(6).

5. Head trauma
It is well known that head trauma may cause hearing loss, which can be either conductive or sensorineural. Benign paroxysmal positional vertigo and olfactory dysfunction due to head trauma are also well known(7).

6. Syphilis
Syphilis is a chronic, systemic and sexually transmitted infectious disease affecting most of the organs in the body. A young African man presented withvertigo, unsteadiness of gait and a skin rash suggestive of secondarysyphilis. Diagnosis was confirmed on serology and was treated with two shots of long-acting penicillin, following which his symptoms settled(8).

7. Benign positional vertigo (BPV) 
Benign positional vertigo (BPV) is the most common cause of episodicvertigo. It results from activation of semicircular canal receptors by the movement of calcium carbonate particles (otoconia) which dislodge from the otolith membranes. During changes in head position, the otoconia either float freely within the semicircular canal duct (canalithiasis) or adhere to and move with the cupula of the canal (cupulolithiasis). BPV from canalithiasis evokes brief spells of vertigo lasting seconds and can be diagnosed at the bedside by provoking paroxysmal vertigo and nystagmus on tilting the head in the plane of the affected canal. The nystagmus has a unique rotational axis perpendicular to the affected canal(9)

B. Risk Factors
1. Endolymphatic hydrops 
In the study to assess the results of treatment for a first episode of benign paroxysmal positional vertigo (BPPV) and risk factors for recurrence at the Kobe University Graduate School of Medicine, showed that  endolymphatic hydrops is a risk factor for recurrence of BPPV and that prevention of recurrent BPPV is important for control of endolymphatic hydrops(10)

2. Vascular risk factors
Vascular risk factors predispose to vertebrobasilar ischemia. Cervical osteophytes can impinge on the vertebral artery causing mechanical occlusion during head turning. Presentation with vertigo in such instances is a common finding(11)


3. Otitis media history
Researchers found that having an otitis media history or eustachian tube dysfunction determined with the nine-step inflation/deflation tympanometric test before diving, or difficulty in clearing ears during diving could be important risk factors for AV in sport SCUBA divers (p <.05)(12).

4. Gender
If you are women, you at  two to three times higher risk to develop Vertigo

5. Vestibular neuritis (VN) is a condition of an ear disorder that involves irritation and inflammation. The recurrence rate of vertigo due to any cause in patients with vestibular neuritis (VN) was about 26.0(13)

6. Heredity
Genetic loci and clinical features of familial episodic ataxias have been defined in linkage disequilibrium studies with mutations in neuronal genes KCNA1 and CACNA1A. Migrainous vertigo is a clinical disorder with a high comorbidity within families much more common in females with overlapping features with episodic ataxia and migraine. Bilateral vestibular hypofunction is a heterogeneous clinical group defined by episodes of vertigo leading to progressive loss of vestibular function which also can include migraine.Meniere’s disease is a clinical syndrome characterized by spontaneous episodes of recurrent vertigo, sensorineural hearing loss, tinnitus and aural fullness and familial Meniere’s disease in around 10-20% of cases.(14)

7. Etc.

IV. Diseases associated with Vertigo
In the study to the DISCUSSION ON VERTIGO, the team wrote that Vertigoassociated with
1. acute, non-perforative otitis media, with
2. chronic otitis media, with 
3. labyrinthine fistula, with  
4. otosclerosis,
5. post-suppurative adhesions; with 
6. peripheral nerve deafness,
7. gun deafness;
8. with rhinitis,  
9. ethmoiditis, 
10. sinusitis, 
11. nasal polypi, 
12. postnasal catarrh and 
13. dental infections.-Influence of general health on recurrent vertigo and vice versa (3)


V. Diagnosis
Dr. Della-Morte D, Rundek T. at the University of Miami, indicated that differential diagnosis between vascular vertigo and other causes of vertigocan result in misclassification due to the overlapping of symptoms. Careful medical history, physical examination, neuroimaging and ear, nose, and throat studies may help to distinguish vascular vertigo from other causes.(1)
1. Positive Dix-Hallpike test.
In the study of Twelve patients from the derivation set and six patients from the validation set had DHT + BPPV. Binomial logistic regression analysis selected a “duration of dizziness ≤15 seconds” and “onset when turning over in bed” as independent predictors of DHT + BPPV with an odds ratio (95% confidence interval) of 4.36 (1.18-16.19) and 10.17 (2.49-41.63), respectively. Affirmative answers to both questions yielded a likelihood ratio of 6.81 (5.11-9.10) for diagnosis of DHT + BPPV, while negative answers to both had a likelihood ratio of 0.19 (0.08-0.47).(15)

2. Electronystagmography versus videonystagmography
In the study to assess the value of electronystagmography (ENG) and videonystagmography (VNG) for diagnosing vertigo of various origin, scientists at the Medical University of Łódź, showed that In all patients withvertigo due to vestibular neuritis, barotrauma and kinetosis, significant CP, the important sign of peripheral site of vestibular lesion was identified both inENG and VNG. None of the patients with central origin disorders showed CP in VNG; in the majority of cases DP was observed. However, in ENG we found CP in 5 patients with central origin disorders. There were no essential differences between ENG and VNG in measurements of FRQ and SPV except for higher values in VNG in controls and patients with mixedvertigo(16)

3. CT scan
CT scan  if a brain injury is suspected to be the cause of vertigo or your doctor would like to rule out the tumors or cancer causes of vertigo.

4. Etc.

VI. Preventions
A. The Do’s and Do not’s list 
1. Unhealthy diet
Unhealthy diet with high in saturated and trans fat and less fruits and vegetables can increase the risk of cholesterol building up in the arteries and nutrients deficiency of that can lead to insufficient blood flow to the back of the brain.

2.  Avoid damage to the head
From a neurotologic perspective, approximately 21.9% of head injuredworkers were determined to have recognizable evidence of cochleovestibular dysfunction. Olfactory dysfunction as a physical finding post-head injury compares favourably with the presence of post-traumatic benign positional paroxysmal vertigo (BPPV) and its atypical variants in 11.2% of head injuredworkers(17)

3. Relaxation
In the study of VERTIGO AND PSYCHOLOGICAL DISTURBANCES  Timothy C. Hain, MD, showed that Psychological abnormalities are common in the general population, even more common in those who are ill, and are certainly also common in individuals with vertigo. In a recent study by Garcia et al in Portugal, out of 43 patients, a large number of psychological abnormalities were diagnosed by the SCL-90 (a standard psychological test) including
a. Somatization     41.9%
b. Hostility     20.9%
c. Interpersonal sensitivity     18.6%
d. Anxiety     23.3%
e. Phobic anxiety     20.9%
f. OCD (obsessive compulsive disorder)     53.5%
g. Depression     30.2%
h. Paranoid traits     11.6%
i. Psychotic traits     2.3%(18)

4. Fruits and vegetables
Fruits and vegetables contain high amount of antioxidants and overprotective nutrients of which can enhance the immune system in fighting against firming of free radicals causes of degenerative diseases and viral and bacteria causes of infection and inflammation and decrease the chronic diseases causes of vertigo.

5. Moderate exercise
Excessive exercise can decrease the immune function in fighting against disease, moderate exercise not only enhances the blood circulation to increase oxygen to the back of the brain but also promotes the immune function fighting against inflammation and weaken immune system causes of vertigo.

6. Smoking
Smoking can reduce the lung function in oxygen absorption, thus reducing the risk of oxygen deficiency causes of vertigo.

7. Excessive alcohol drinking
Alcoholism can weaken the immune system and increase the risk of inflammatory causes of vertigo.

8. Etc.

B. Diet
 against vertigo
1. Mushroom
Mushroom is a standard name of white button mushroom, the fleshy, spore-bearing fruiting body of a fungus produced above ground on soil or on its food source, It is a genus A. Muscaria and belong to the family Amanitaceae and has been cultivation in many cultures all over the world for foods and health benefits.
a. Immunologic effects
In the analyzing White button mushrooms (WBM) and its effect in immune response, found that WBM promote DC maturation and enhance their antigen-presenting function. This effect may have potential in enhancing both innate and T cell-mediated immunity leading to a more efficient surveillance and defense mechanism against microbial invasion and tumor development, according to “White button mushroom enhances maturation of bone marrow-derived dendritic cells and their antigen presenting function in mice” by Ren Z, Guo Z, Meydani SN, Wu D.(36)

b. Neurotrophic action
Found that
the neurotrophic action of cobalamin (Cbl) in the central nervous system (CNS) of totally gastrectomized (TGX) rats is mediated by stimulation of the epidermal growth factor(EGF) synthesis in the CNS itself. It thus appears that Cbl inversely regulates the expression of EGF and TNF-alpha genes in the CNS of TGX rats, according to “Epidermal growth factor as a local mediator of the neurotrophic action of vitamin B(12) (cobalamin) in the rat central nervous system” by Scalabrino G, Nicolini G, Buccellato FR, Peracchi M, Tredici G, Manfridi A, Pravettoni G.(37)

c. Copper
Copper is best known for its function in regulating the proper growth, utilization of iron, it is also a strong antioxidant, aiding the antioxidant enzyme, superoxide dismutase, and preventing oxidation in the cell membrane, according to the article of antioxidant cancer and diseases, posted in(38)

d. Cholesterol Levels
Since it contains high amount of fiber, it not only helps to bind the bad cholesterol (LDL) in the digestive track then expelling them through normal waste release, but also burns cholesterol when they are digested because of its high lean protein content., according to the study of “Fiber intake, serum cholesterol levels, and cardiovascular disease in European individuals with type 1 diabetes. EURODIAB IDDM Complications Study Group” by Toeller M, Buyken AE, Heitkamp G, de Pergola G, Giorgino F, Fuller JH., (39)

e. Immune system
Since it contain high amount of vitamin C, it not only helps to improve the immune system in fighting against the foreign invasion, such as virus and bacteria, but also helps to inhibits fatty acid synthase expression as a result of the presence linoleic acid, thus reducing the risk of tumors and breast, colon and prostate cancers, according to the study of “The 10t,12c isomer of conjugated linoleic acid inhibits fatty acid synthase expression and enzyme activity in human breast, colon, and prostate cancer cells” by Lau DS, Archer MC.,(40)

2. Cabbage is a spicies of Brassica oleracea belong to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. It has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.
a. Cardiovascular health
Cabbage in steam cooking and other vegetable such as collard greens, kale, mustard greens, broccoli, green bell pepper has exerted the ability in lowering the recirculation of bile acids results in utilization of cholesterol to synthesize bile acid and reduced fat absorption and may be beneficial in preventing cardiovascular disease, cancer and improve public health, according to the study of “Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage” by Kahlon TS, Chiu MC, Chapman MH.(41)

b.  Vitamin K
Degenerative diseases of ageing
Long-term vitamin K inadequacy may reduce the function of supporting the carboxylation of at least some of these Gla-protein that can lead the development of degenerative diseases of ageing including osteoporosis and atherosclerosis, according to the study of “Vitamin K, osteoporosis and degenerative diseases of ageing” by Cees Vermeer and Elke Theuwissen(42)


c. Omega 3 fatty acid
Cabbage reduces the risk of cardiovascular diseases by controlling the secretion of bad cholesterol, due to high amount of Omega 3 fatty acid, according to the study of “The Omega-3 Index as a risk factor forcardiovascular diseases‘ by von Schacky C.(43)


3. Kiwifruit also best hnown as kiwi or Chinese gooseberry, is a species of A. chinensis belong to the family Actinidia, subgroup of the flavonoids and native to Southern China.
a. Type 2 diabetes
In the investigation of six kinds of fruits tested were grapes, Asian pears, guavas, golden kiwifruit, lychees and bananas and their glycemic index found that there was no significant difference in glycemic index values between healthy and Type 2 diabetes subjects. There was also no significant difference in PII when comparing healthy subjects and subjects with Type 2 diabetes and concluded that glycemic index and peak incremental indices in healthy subjects can be approximately the same for Type 2 diabetes, according to “Glycemia and peak incremental indices of six popular fruits in Taiwan: healthy and Type 2 diabetes subjects compared” by Chen YY, Wu PC, Weng SF, Liu JF.(44)


b. Vitamin C
Besides is essential in preventing the breaking off small vein cause of hardening of the vessel wall, vitamin C also improves the digestive system in maximum absorption of vital nutrients. Overdoses can cause diarrhea, It also plays an important role in enhancing immune system fighting against the forming of free radicals that cause muscle damage, according to the study of “Does antioxidant vitamin supplementation protect against muscle damage?” by McGinley C, Shafat A, Donnelly AE.,(45)


c. Antioxidants
 Since kiwifruit contains high amount of Vitamin C, it helps to enhance the immune function in fighting against forming of free radicals, thus reducing the risk of irregular cell growth, such as tumor and cancer, according to the study of “High-dose vitamin C (ascorbic acid) therapy in the treatment of patients with advanced cancer” by Ohno S, Ohno Y, Suzuki N, Soma G, Inoue M.(46)


4.  Olive Oil
Olive is belongs to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is also called the olive and the source of olive oil.
a. Cardiovascular health
In the investigation of
the olive oil of the primary source of fat used in Mediterranean diet, found that olive oil consumption could contribute to explaining the low rate of cardiovascular mortality found in southern European-Mediterranean countries, according to “Olive oil andcardiovascular health” by Covas MI, Konstantinidou V, Fitó M.(47)

b. Antioxidants and weight loss
In the
analyzing the influence of a Mediterranean dietary pattern on plasma total antioxidant capacity (TAC) found that Mediterranean diet, especially rich in virgin olive oil, is associated with higher levels of plasma antioxidant capacity. Plasma TAC is related to a reduction in body weight after 3 years of intervention in a high cardiovascular risk population with a Mediterranean-style diet rich in virgin olive oil, according to “A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain” by Razquin C, Martinez JA, Martinez-Gonzalez MA, Mitjavila MT, Estruch R, Marti A.(48)

c. Healthy effect of virgin olive oil
According to “
International conference on the healthy effect of virginolive oil” by

Perez-Jimenez F, Alvarez de Cienfuegos G, Badimon L, Barja G, Battino M, Blanco A, Bonanome A, Colomer R, Corella-Piquer D, Covas I, Chamorro-Quiros J, Escrich E, Gaforio JJ, Garcia Luna PP, Hidalgo L, Kafatos A, Kris-Etherton PM, Lairon D, Lamuela-Raventos R, Lopez-Miranda J, Lopez-Segura F, Martinez-Gonzalez MA, Mata P, Mataix J, Ordovas J, Osada J, Pacheco-Reyes R, Perucho M, Pineda-Priego M, Quiles JL, Ramirez-Tortosa MC, Ruiz-Gutierrez V, Sanchez-Rovira P, Solfrizzi V, Soriguer-Escofet F, de la Torre-Fornell R, Trichopoulos A, Villalba-Montoro JM, Villar-Ortiz JR, Visioli F. indicated that
c.1. Ageing represents a great concern in developed countries because the number of people involved and the pathologies related with it, like atherosclerosis, morbus Parkinson, Alzheimer’s disease, vascular dementia, cognitive decline, diabetes and cancer.
c.2. Epidemiological studies suggest that a Mediterranean diet (which is rich in virgin olive oil) decreases the risk of cardiovascular disease.
c.3. The Mediterranean diet, rich in virgin olive oil, improves the major risk factors for cardiovascular disease, such as the lipoprotein profile, blood pressure, glucose metabolism and antithrombotic profile. Endothelial function, inflammation and oxidative stress are also positively modulated. Some of these effects are attributed to minor components of virgin olive oil. Therefore, the definition of the Mediterranean diet should include virgin olive oil.
c.4. Different observational studies conducted in humans have shown that the intake of monounsaturated fat may be protective against age-related cognitive decline and Alzheimer’s disease.
c.5. Microconstituents from virgin olive oil are bioavailable in humans and have shown antioxidant properties and capacity to improve endothelial function. Furthermore they are also able to modify the haemostasis, showing antithrombotic properties.
c.6. In countries where the populations fulfilled a typical Mediterranean diet, such as Spain, Greece and Italy, where virgin olive oil is the principal source of fat, cancer incidence rates are lower than in northern European countries.
c.7. The protective effect of virgin olive oil can be most important in the first decades of life, which suggests that the dietetic benefit of virgin olive oilintake should be initiated before puberty, and maintained through life.
c.8. The more recent studies consistently support that the Mediterranean diet, based in virgin olive oil, is compatible with a healthier ageing and increased longevity. However, despite the significant advances of the recent years, the final proof about the specific mechanisms and contributing role of the different components of virgin olive oil to its beneficial effects requires further investigations.(49)
5. Lean beef are considered as animal fresh of which most fats are withdrawn before consuming to reduce the amount of sutured fat and cholesterol. Although some people insist that meats with fat are highly tasty, but the consequence of eating too much fat can damp the health of your body, leading to all kinds of diseases. Because of the use of growth hormone and selective breeding for commercial purposes, it is advised only eating lean meats from organic farm.
a. Nutrients
In the assessment of the nutrients in lean beef found that
Total beefconsumed among adults 19 to 50 and 51+ years was 49.3 +/- 1.4 g (1.74 oz/d) and 37.1 +/- 1.2 g (1.31 oz/d), respectively. In adults 19 to 50 and 51+ years, LB contributed 3.9% and 3.7% to total energy; 4.5% and 4.1% to total fat, 3.8% and 3.6% to saturated fatty acids; 13% and 11% to cholesterol intake; 15% and 14% to protein; 25% and 20% to vitamin B(12); 23% and 20% to zinc; and 8% and 7% to iron, respectively. Beef was also an important food source of many other nutrients, including niacin, vitamin B(6), phosphorus, and potassium. In addition, beef provided only 1% of total sodium intake and concluded that Consumption of beef contributed significantly to intake of protein and other key nutrients by US adults, according to “Lean beef contributes significant amounts of key nutrients to the diets of US adults: National Health and Nutrition Examination Survey 1999-2004″ by Zanovec M, O’Neil CE, Keast DR, Fulgoni VL 3rd, Nicklas TA.(50)
b. Cardiovascular health
In the examination of
the effects of dietary protein intake on energy restriction (ER)-induced changes in body mass and body composition found that overweight postmenopausal women can achieve significant weight loss and comparable short-term improvements in body composition and lipid-lipoprotein profile by consuming either a moderate-protein (25% of energy intake) poultry- or beef-containing diet or a lacto-ovo vegetarian protein (17% of energy intake) diet, according to “Protein intake during energy restriction: effects on body composition and markers of metabolic andcardiovascular health in postmenopausal women” by

Mahon AK, Flynn MG, Stewart LK, McFarlin BK, Iglay HB, Mattes RD, Lyle RM, Considine RV, Campbell WW.(51)
c. Diabetes
In random sequence, 50 g protein in the form of very lean beef or only water at 0800 h and studied over the subsequent 8 h found that the amount of glucose appearing in the circulation was only approximately 2 g. The peripheral plasma glucose concentration decreased by approximately 1 mM after ingestion of either protein or water, confirming that ingested protein does not result in a net increase in glucose concentration, and results in only a modest increase in the rate of glucose disappearance, according to “Effect of protein ingestion on the glucose appearance rate in people with type 2diabetes” by Gannon MC, Nuttall JA, Damberg G, Gupta V, Nuttall FQ.(52)
d. Improve the nutrient transportation
The high levels of iron helps in maintaining high levels of energy and oxygen through the bloodstream as it enhances the function of blood in oxygen absorption, reduces the risk of iron deficiency anemia and improves the menstrual health for teenage girls and women in their child-bearing years, according to the study of “[Menstrual blood loss and iron nutritional status in female undergraduate students].[Article in Chinese]” by Li J, Gao Q, Tian S, Chen Y, Ma Y, Huang Z., posted in PubMed(53)
6. Sardines are several types of small, salt-water, soft-boned small oily fish in the family Clupeidae. There are as many as 21 species can be classified as sardines and their main food is plankton on the surface of the water. They are commercially fished for foods and variety of uses, including animal feed, sardine oil used in manufacture paint, varnish and linoleum.
a.  cardiovascular diseases
In the investigation of the nutritional benefits of fish consumption relate to the utilization of proteins of high biological value, as well as certain minerals and vitamins of fish found that The top 11 fish species [e.g., sardines, mackerel, herring (Atlantic and Pacific), lake trout, salmon (Chinook, Atlantic, and Sockeye), anchovy (European), sablefish, and bluefish] provide an adequate amount of omega-3 PUFAs (2.7-7.5g/meal) and appear to meet the nutritional recommendation of the American Heart Association, according to “Healthbenefits and potential risks related to consumption of fish or fish oil” by Sidhu KS.(54)

b. Cardiometabolic syndrome
In the research of Ogema 3 fatty acids (Found abundantly in sardine) and its effect in reducing cardiometabolic syndrome risk factors found that consumption of fish or fish oil containing omega-3 polyunsaturated fatty acids reduces the risk of coronary heart disease, decreases triglyceride, blood pressure, and inflammatory markers, improves endothelial function, prevents certain cardiac arrhythmias, reduces platelet aggregation (including reactivity and adhesion), reduces vasoconstriction, enhances fibrinolysis, reduces fibrin formation, and decreases the risk of microalbuminuria and sudden cardiac death. Thus, fish intake or fish oil supplement use is beneficial to reduce cardiometabolic risk factors, according to “Omega-3 fatty acids and the cardiometabolic syndrome” by Juturu V.(55)

c. Glucose tolerance
In the observation of an enzymatic hydrolysate of sardine protein (sardinepeptide, SP) derived from sardine muscle possesses angiotensin I-converting enzyme (ACE) inhibitory activity, found that treatment with SP and captopril decreased ACE activity in the kidney, aorta, and mesentery. SP and captopril administration significantly suppressed the increase in blood glucose after glucose loading in the control SHRSPs, according to “Sardine peptide with angiotensin I-converting enzyme inhibitory activity improves glucose tolerance in stroke-prone spontaneously hypertensive rats” by Otani L, Ninomiya T, Murakami M, Osajima K, Kato H, Murakami T.(56)

d. Anti-Hyperleptinemia and anti- inflammation
In the exploring the effects of sardine protein on insulin resistance, plasma lipid profile, as well as oxidative and inflammatory status in rats with fructose-induced metabolic syndrome found that Sardine protein diets also prevented hyperleptinemia and reduced inflammatory status in comparison with rats fed casein diets, according to “Dietary sardine protein lowers insulin resistance, leptin and TNF-α and beneficially affects adipose tissue oxidative stress in rats with fructose-induced metabolic syndrome” by Madani Z, Louchami K, Sener A, Malaisse WJ, Ait Yahia D.(57)

7. Etc.

 


C. Antioxidants Against vertigo
1. Carotenoids
Carotenoids are organic pigments, occurring in the chloroplasts and chromoplasts of plants and some other photosynthetic organisms like algae, some bacteria.
a. Beta-carotene
Beta-Carotene, an organic compound and classified as a terpenoid, a strongly-coloured red-orange pigment in plants and fruits.
a.1. It is not toxic and stored in liver for the production of vitamin A that inhibits cancer cell in experiment. Beta-carotene also neutralize singlet oxygen before giving rise of free radicals which can damage of DNA, leading to improper cell DNA replication, causing cancers.
a.2. Cell communication
Researcher found that beta-carotene enhances the communication between cell can reduce the risk of cancer by making cells division more reliable.
a.3. Immune system
Beta-carotene promotes the immune system in identifying the foreign invasion such as virus and bacteria by increasing the quality of MHC2 protein in maintaining optimal function of white cells.
a.4. Polyunsaturated fat
Researchers found that beta-carotene also inhibits the oxidation of polyunsaturated fat and lipoprotein in the blood that reduce the risk of plaques build up onto the arterial walls, causing heart diseases and stroke.
a.5. There are more benefits of beta-carotene.

b. Alpha-carotene
Alpha-carotene, one of the most abundant carotenoids in the North American diet, is a form of carotene with a β-ring at one end and an ε-ring at the other. It is the second most common form of carotene which not only protects cells from the damaging effects of free radicals and enhances the immune system in fighting against bacteria and virus invasion, but also stimulates the communication between cells thus preventing irregular cell growth cause of cancers.

c. Beta-cryptoxanthin
Beta cryptoxanthin is an antioxidant, beside helping to prevent free radicaldamage to cells and DNA but also stimulates the repair of oxidative damage to DNA. it enhances the immune function infighting against inflammatory cause of polyarthritis, and irregular cell growth cause of cancer due to oxidation.

d. Lutein
Lutein is one of the most popular North American carotenoids. It is found in greens like kale and spinach as well as the yolk of eggs. Lutein is also found in the human eye. Getting enough lutein in your diet may help to fight off age related macular degeneration, an eye condition.
Researcher has shown that people who do not have enough lutein in their diet will not have enough lutein present in the muscular part of the eye. This is what likely leads to age related macular degeneration that can result in blindness.

e. Zeaxanthin
Zeaxanthin, a most common carotenoid alcohols found in nature, is one of the two primary xanthophyll carotenoids contained within the retina of the eye. Intake of foods providing zeaxanthin with lower incidence of age-related macular degeneration as a result of its function of reducing the risk oxidative stress.

f. Lycopene
Lycopene is a red carotene of the carotenoid group that can be found in tomatoes, watermelons, and grapefruits. This powerful antioxidant is believed to be a powerful fighter of prostate cancer. Lycopene has many anti-aging capabilities as well as one of the most powerful antioxidants in the carotenoid group.

2. Antioxidants and Atherosclerosis
a. Bioflavonoids or vitamin P
Discovered by Szent-Gyorgyi and his colleagues back in the 1930`s. In Laboratory tests, B
bioflavonoids help to reduce the fragility and “permeability” in capillaries and prevent the clotting up of arterial as a result of oxidation.

b. Vitamins C and E, beta-carotene
Recent research findings have suggested that antioxidants such as vitamin C, E and beta carotene play an important role in the prevention of atherosclerosis. Data from animal studies showed they are able to prevent oxidative modification of low density lipoproteins (LDL).

c. Alpha-tocopherol
Alpha-tocopherol, a antioxidant found abundant in vitamin E, helps to decrease lipid peroxidation and platelet aggregation, adhesion and inflammatory. Epidemiological studies suggest that low levels of antioxidants are associated with increased risk for cardiovascular disease.

d. Vitamin C and E
Studies showed in take of 500mg of vitamin C and 400 IU of vitamin E helps to retard the progression of coronary atherosclersis.

e. Chlorophyl
Antioxidant chorophyll in the green algae shows to inhibit the chemical cadmium of smoking, by preventing from oxidation that cause building up of plaque along the walls of arteries.

3. Antioxidants and Multiple sclerosis
Antioxidants can help protect the neural tissue from damage that reduce the risk of inflammation result in lessening the risk of oxidative stress.
a. TNFalpha
An imflammatory cytokine has been associated with MS is inhibited by antioxidants of green tea, and others such as curcumin, quercetin, etc.

b. Melatonin
Melatonin functions as an antioxidant and has the ability to protect neurons from free radicals cause of lipid peroxidation.

c Selenium
Some studied found that the levels of selenium in the blood of people with MS was lower than in that of people without MS.

d. Niacin
Niacin acts as antioxidant is a key to the successful treatment of multiple sclerosis, researchers at Harvard Medical School found that Niacin profoundly prevents the degeneration of demyelinated axons and improves the behavioral deficits.

e. Vitamin D
A study published in a recent issue of the journal Neurology, the group receiving the vitamin D demonstrated a remarkable 41 percent reduction in new MS events with no meaningful side effects.

f. Etc.

4. Antioxidants and diabetes
a. a. Alloxam
Invitro and vivo study found that hydroxyl radical scavengers, metal chelation and fat soluble antioxidants inhibit the damage caused by Alloxam.

b. Vitamin E
Study also found that vitamin E can prevent the development of Alloxam induced diabetes by administrating butylated hydroxyanisole, an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole & 3-tert-butyl-4-hydroxyanisole.

c. Vitamin C
Depress levels of vitamin C is found in diabestic. as we know vitamin C compete with glucose in transported in the cell via insulin. low levels of vitamin C also elevates sorbitol, leading to diabetic complication.

d. Alpha-lipoic acid
Alpha-lipoic acid beside lower the levels of blood sugar, it also destroys free radicals that help to reduces symptoms and complication caused by diabetes, including peripheral neuropathy.

e. Etc.

5. Antioxidants and immune system
Enzyme antioxidants, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase are best known to defense our body in fighting or scavenging against forming of free radicals by neutralizing them. Other antioxidants include
a. Zinc
Zinc, as a antioxidant is essential mineral in ading immune system by enhancing the peoper function of T cells which belong to a group of white blood cells known as lymphocytes, in fighting against damaging free radicals.

b. Selenium
Selenium is one of the powerful antioxidant. In the extracellular space, it helps to influence immune processes by proliferating the response to mitogen, and macrophages, leukotriene.

c. Vitamin A
vitamin A plays an essential roles in enhancing a broad range of immune processes, including lymphocyte activation and proliferation, T-helper-cell differentiation, the production of specific antibody isotypes and regulation of the immune response.

d. Vitamin C
Researchers found that vitamin C raised the concentration in the blood of immunoglobulin A, M that promotes the ability of antibodies and phagocytic cells to clear pathogens.

e. Vitamin E
In aged mice study showed that Vitamin E beside increased both cell-dividing and IL-producing capacities of naive T cells it also enhances the immune functions in association with significant improvement in resistance to influenza infection.

f. Carotenoids
Carotenoids reduces oxidation damage to cells and protects LDL cholesterol from oxidation, thus reducing the risk of aging and chronic diseases caused by damaging free radicals.

g. Etc.

D. Phytochemicals against vertigo
1. Rutin also known as rutoside, quercetin-3-O-rutinoside and sophorin is aFlavonols, belong to Flavonoids (polyphenols) of Phenolic compounds found orange, grapefruit, lemon, lime, berries mulberry, cranberries, buckwheat etc.
a. Anti-inflammatory activity
In the investigation of Rutin, a natural flavone derivative and its anti inflammatory effect found that Oral administration of rutin reduced rat paw swelling starting 2 hours after lambda-carrageenan injection. Rutin reduced significantly (p < 0.05) and in a dose-dependant manner the polymorphonuclear neutrophils chemotaxis to fMet-Leu-Phe, according to the study of “Anti-inflammatory effect of rutin on rat paw oedema, and on neutrophils chemotaxis and degranulation” by Selloum L, Bouriche H, Tigrine C, Boudoukha C.(19)

b.  Diabetes-increased aging effect
In the observation of 1 g.kg-1.day-1 rutin, an aldose reductase inhibitor and irs effect on products from the advanced Maillard reaction which increase during aging and diabetes found that even though rutin prevent the accumulation of fluorescence are unknown, but these observations raise the question of whether they could be identical. If fluorescence is a marker for age-related pathologies and diabetic sequelae, aminoguanidine and rutincould have therapeutic effects in their prevention, according to “Prevention ofdiabetes-increased aging effect on rat collagen-linked fluorescence by aminoguanidine and rutin” by Odetti PR, Borgoglio A, De Pascale A, Rolandi R, Adezati L.(20)

c. Diabetes, Hyperglycemia and dyslipidemia
In the analyzing Dietary antioxidant compounds such as flavonoids and its protection against early-stage diabetes mellitus, found that Rutin (50 mg kg(-1)) reduced (p<0.05) blood glucose and improved the lipid profile in STZ-induced diabetic rats and concluded that that rutin can improve hyperglycemia and dyslipidemia while inhibiting the progression of liver and heart dysfunction in STZ-induced diabetic rats, acccording to “Influence ofrutin treatment on biochemical alterations in experimental diabetes” byFernandes AA, Novelli EL, Okoshi K, Okoshi MP, Di Muzio BP, Guimarães JF, Fernandes Junior A.(21)

d. Fatty liver disease
In evaluation of rutin, a common dietary flavonoid and the hypolipidemic effect of it on fatty liver disease found that rutin could attenuate lipid accumulation by decreasing lipogenesis and oxidative stress in hepatocyte, according to “Rutin inhibits oleic acid induced lipid accumulation via reducing lipogenesis and oxidative stress in hepatocarcinoma cells” by Wu CH, Lin MC, Wang HC, Yang MY, Jou MJ, Wang CJ.(22)

e. Cardiovascular health
In the testing the hypothesis of the consumption of a diet rich in flavonoids can be associated with a reduced risk for cardiovascular disease found that hamster fed with 2% cranberry concentrate powder (HFHC+CE); a HFHC with 0.1% rutin (HFHC+Rutin); and a HFHC with 30 mg/kg vitamin E (HFHC+Vit.E) diet for either 12 or 20 weeks, found that Ratios of plasma high-density lipoprotein cholesterol (HDL-C) to very-low-density lipoprotein cholesterol and of plasma HDL-C to low-density lipoprotein cholesterol were significantly higher in animals consuming HFHC+Vit.E, according to the strudy of “Effects of a flavonol-rich diet on select cardiovascularparameters in a Golden Syrian hamster model” by Kalgaonkar S, Gross HB, Yokoyama W, Keen CL.(23)

f.  Periodontal disease
In the study of isolation from the mouths of 2 healthy subjects, hydrolysed innocuous rutin, a flavonoid glycoside, to its genotoxic aglycon quercetin and its effect on local carcinogenic process found that a hypothesis for a novel role of the oral microflora in a disease process other than caries and periodontal disease, namely intra-oral cancer, is presented. The possibility of a bacterial liberation of the genotoxic quercetin in situ could be but one example of its involvement in the local carcinogenic process, according to “Activation of rutin by human oral bacterial isolates to the carcinogen-mutagen quercetin” by Parisis DM, Pritchard ET.(24)

2. Naringenin, a flavanone, belonging to the red, blue, purple pigments of Flavonoids (polyphenols) found predominantly in citrus fruits is considered as one of powerful antioxiant with many health benefits.
a. Antioxidant, radical scavenging and biomolecule activity
In the affirmation of the capacity of flavonoid naringenin and its glycoside naringin in the comparison of theirs antioxidant capacities, radical scavenging and biomolecule activities found that naringenin exhibited higher antioxidantcapacity and hydroxyl and superoxide radical scavenger efficiency than naringin and both flavanones were equally effective in reducing DNA damage. However, they show no protective effect on oxidation of GSH, according to the study of “Antioxidant properties, radical scavenging activity and biomolecule protection capacity of flavonoid naringenin and its glycoside naringin: a comparative study” by Cavia-Saiz M, Busto MD, Pilar-Izquierdo MC, Ortega N, Perez-Mateos M, Muñiz P.(25)

c. Cholesterol-lowering activity
In the affirmation of naringenin and its Cholesterol-lowering effect found thatnaringenin lowers the plasma and hepatic cholesterol concentrations by suppressing HMG-CoA reductase and ACAT in rats fed a high-cholesteroldiet, according to “Cholesterol-lowering activity of naringenin via inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase and acyl coenzyme A:cholesterol acyltransferase in rats” by Lee SH, Park YB, Bae KH, Bok SH, Kwon YK, Lee ES, Choi MS.(26)

d. Anti-inflammatory effects
In the evaluation of the mechanisms of action of the effective compounds. Flavone, the isoflavones daidzein and genistein, the flavonols isorhamnetin, kaempferol and quercetin, the flavanone naringenin, and the anthocyanin pelargonidin amd theirs anti-inflammatory effects found that they inhibited iNOS protein and mRNA expression and also NO production in a dose-dependent manner, according to “Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages” by Hämäläinen M, Nieminen R, Vuorela P, Heinonen M, Moilanen E.(27)

e. Immunity
In the unvestigation of Naringenin, a flavonoid in grapefruits and citrus fruits and its effec in immune system found that naringenin potently suppressed picryl chloride (PCl)-induced contact hypersensitivity by inhibiting the proliferation and activation of T lymphocytes. In vitro, both of the activated hapten-specific T cells and the T cells stimulated with anti-CD3/anti-CD28 showed growth arrest after naringenin treatment, according to “A novel regulatory mechanism of naringenin through inhibition of T lymphocyte function in contact hypersensitivity suppression” by Fang F, Tang Y, Gao Z, Xu Q.(28)

3. Catechin is phytochemical of Flavan-3-ols, in the group of Flavonoids (polyphenols), found abundantly in white tea, green tea, black tea, grapes, wine, apple juice, cocoa, lentils, etc.
a. Cholesterol
In a systematic review and meta-analysis of randomized controlled trials evaluating the relationship between GTCs and serum lipid levels, including total, low-density lipoprotein (LDL), high-density lipoprotein (HDL) cholesterol, and triglycerides, found that the consumption of GTCs is associated with a statistically significant reduction in total and LDL cholesterol levels; however, there was no significant effect on HDL cholesterol or triglyceride levels, according to ” Green tea catechins decrease total and low-density lipoprotein cholesterol: a systematic review and meta-analysis” by Kim A, Chiu A, Barone MK, Avino D, Wang F, Coleman CI, Phung OJ.(29)

b. Antioxidant activity
In the research on polyphenolic compounds (included catechins) in the berries of edible honeysuckle and their biological effects, including recommended utilization, are reviewed found that These berries seem to be prospective sources of health-supporting phytochemicals that exhibit beneficial anti-adherence and chemo-protective activities, thus they may provide protection against a number of chronic conditions, e.g., cancer, diabetes mellitus, tumour growth or cardiovascular and neurodegenerative diseases, according to “Phenolic profile of edible honeysuckle berries (genus lonicera) and their biological effects” by Jurikova T, Rop O, Mlcek J, Sochor J, Balla S, Szekeres L, Hegedusova A, Hubalek J, Adam V, Kizek R.(30)

c. Severe dyslipidemia
In the observation of three-month old ATX mice were treated, or not, for 3 months with the polyphenol (+)-catechin (CAT, 30 mg/kg/day) and compared to wild-type (WT) controls,
found that cctive remodeling of the cerebrovascular wall in ATX mice was further suggested by the increase (P<0.05) in pro-metalloproteinase-9 activity, which was normalized by CAT. We conclude that by preserving the endothelial function, a chronic treatment with CAT prevents the deleterious effect of severe dyslipidemia on cerebral artery wall structure and biomechanical properties, contributing to preserving resting cerebral blood flow, according to “Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow” by Bolduc V, Baraghis E, Duquette N, Thorin-Trescases N, Lambert J, Lesage F, Thorin E.(31)

d. Anti-inflammatory effect
In the preparation of the gel of Chinese medicine catechu, and to observe the release mechanism in vitro and anti-inflammatory activity in rats, found that the optimum condition of extraction from catechu was as follows, the concentration of ethanol, ratio of raw material to solvent, ultrasonic time, and extraction temperature were 50% , 1: 12, 35 min and 60 degrees C, respectively. The formulation of catechu gel was carbomer-9 400.5 g, glycerol 5.0 g, the extracts of catechu 50.0 mL, and triethanomine 0.5 mL The gel was semitransparent and stable. The drugs released quickly. The catechu gel reduced the paw edema considerably in dose-dependent manner compared to carrageenan-induced rat, according to “[Preparation and pharmacodynamics studies on anti-inflammatory effect of catechu gel].[Article in Chinese]” by Zheng X, Zheng C.(32)

4. Flavanonols (with two “o”s aka 3-hydroxyflavanone or 2,3-dihydroflavonol) are a class of flavonoids that use the 3-hydroxy-2,3-dihydro-2-phenylchromen-4-one (IUPAC name) backbone(a), found in Japanese Raisin Tree, the wood of Pinus sibirica, Prunus domestica, brazilian green propolis, Black mulberry, etc.
a. Antioxidant capacity
In the determination of the antioxidant of the polyphenolic constituents in some fruits, using the total oxidant scavenging capacity (TOSC) assay, found that cutite showed the highest antioxidant capacity followed by jambolão, araçá, and muruci and antioxidant turned out to be primarily good sources of hydrolyzable tannins and/or flavonols, according to “Phenolic constituents and antioxidant capacity of four underutilized fruits from the Amazon region”by Gordon A, Jungfer E, da Silva BA, Maia JG, Marx F.(33)

b. Anti viral effects
In testing several flavonoids effects on Moloney murine leukemia virus reverse transcriptase activity and studies of four groups of flavonoids, namely flavones, flavanones, flavonols, and flavanonols, found that flavonols and flavanonols were very active in this regard while flavones and flavanones displayed very low activity, according to “Inhibitory effects of flavonoids on Moloney murine leukemia virus reverse transcriptase activity” by Chu SC, Hsieh YS, Lin JY.(34)

c. Anti inflammatory effects
In the examination in a double-blind intervention study conducted with two groups of non-smoking, un-treated sarcoidosis patients, matched for age and gender. One group was given 4×500 mg quercetin (n = 12) orally within 24 h, the other one placebo (n = 6). Plasma malondialdehyde levels were used as marker of oxidative damage, plasma ratios of TNFα/IL-10 and IL-8/IL-10 as pro-inflammatory markers, found that Sarcoidosis patients might benefit from the use of antioxidants, such as quercetin in the group of Flavonols, to reduce the occurring oxidative stress as well as inflammation. The effects of long-term use of antioxidant supplementation in sarcoidosis, using e.g. quercetin, on improvement of lung function remain to be investigated, according to “Quercetin reduces markers of oxidative stress andinflammation in sarcoidosis” by Boots AW, Drent M, de Boer VC, Bast A, Haenen GR.(35)

d. Etc.

5. Etc.

V. Treatments
A. In conventional medicine perspective 
1. Manoeuvres
The most common Epley maneuver is performed by a doctor, audiologist, physical therapist, or with a BPPV maneuver at home. Dr, and the research team at in the study of Diagnosis and treatment of 318 benign paroxysmal positional vertigo cases, suggested that 318 patients, 221 (69.5%) with posterior semicircular canal involvement, Epley repositioning maneuver was performed; 62 (19.5%) with horizontal semicircular canal involvement, Barbecue maneuver combined forced prolonged position maneuver were applied; 23 (7.2%) with anterior canal involvement were treated with Epleymaneuver; 12 (3.8%) had the mixed type and were treated with corresponding repositioning maneuvers. After one week the total improvement rate was 82.1% (261/318) and 91.8% three months later (292/318)(58).

Some researchers suggested that Prevention begins by maintaining good hydration and avoiding rapid movements of the head can be helpful. Researchers at the Università degli Studi di Palermo, indicated that Gufoni’s manoeuvre is effective in treating patients suffering from BPPV of LSC; it is simple to perform; there are not many movements to execute, it needs low time of positioning, and positions are comfortable to the patient(59). Others suggested that Vannucchi maneuver and Log Roll. For more information of the above. (60)

2. Postural restriction therapy
The treatment of benign paroxysmal positional vertigo (BPPV) consists of arepositioning maneuver in order to remove otoliths from the posterior semicircular canal and subsequent postural restrictions to prevent debris from reentering the canal.but researchers at Chonnam National University Medical School and other showed that Postural restriction therapy, practiced after the modified Epley repositioning maneuver, did not have a significant effect on the final outcomes of BPPV. Based on our results, we do not recommend this therapy since there was no significant benefit for the patients who utilized postural restrictions(61).

3. Vestibular training (VT)
In the  study on treatment effects of vestibular training (VT) for benign paroxysmal positional vertigo was performed. The VT was compared with courses of patients in three different groups: patients treated by medication, by VT, and by VT with medication during 8 weeks. Dr. Fujino A and the team of reserachers at Kitasato University found that  In the groups treated by VT, the effects were not influenced by time since onset of disease or by patient age. It is therefore assumed that VT can be used as a first-choice treatment in patients with benign paroxysmal positional vertigo, even in long-term cases or older patients(65).

3. Medication
Certain medication are used in treating vertigo depending to the underlying cause. Dr Hain TC, and Dr. Uddin M. at the , Northwestern University indicated that therapy of vertigo is optimised when the prescriber has detailed knowledge of the pharmacology of medications being administered as well as the precise actions being sought. There are four broad causes of vertigo, for which specific regimens of drug therapy can be tailored. Otological vertigoincludes disorders of the inner ear such as Ménière’s disease, vestibular neuritis, benign paroxysmal positional vertigo (BPPV) and bilateral vestibular paresis. In both Ménière’s disease and vestibular neuritis, vestibular suppressants such as anticholinergics and benzodiazepines are used. InMénière’s disease, salt restriction and diuretics are used in an attempt to prevent flare-ups. In vestibular neuritis, only brief use of vestibular suppressants is now recommended. Drug treatments are not presently recommended for BPPV and bilateral vestibular paresis, but physical therapy treatment can be very useful in both. Central vertigo includes entities such asvertigo associated with migraine and certain strokes. Prophylactic agents (L-channel calcium channel antagonists, tricyclic antidepressants, beta-blockers) are the mainstay of treatment for migraine-associated vertigo. In individuals with stroke or other structural lesions of the brainstem or cerebellum, an eclectic approach incorporating trials of vestibularsuppressants and physical therapy is recommended. Psychogenic vertigooccurs in association with disorders such as panic disorder, anxiety disorder and agoraphobia. Benzodiazepines are the most useful agents here(62).
Other researchers suggested that treatment by medication together with two maneuvers-the particle repositioning maneuver (PRM) reported by Parnes and Price-Jones and the liberatory maneuver (LM) reported by Semont et al.-were compared with treatment by medication alone. The most important benefit of these maneuvers seemed to be the speedier recovery than with medicationalone, as there was no significant difference in the late success rate after 3 months between the maneuvers and medication alone(63).

4. Surgery (Tenotomy)
In the study to compare the unique long-term results of tenotomy of the stapedius and tensor tympani muscles in definite Meniere’s disease refractory to medical treatment and presents a hypothesis on why tenotomy seems effective, Dr. Loader B, and the research team at Medical University of Vienna showed that a statistically significant improvement of inner ear hearing levels postoperatively (p = 0.041) and a major reduction in vertigoattacks in all groups (p < 0.001) with complete absence of attacks in 26/30 patients was noted. Results remained constant up to 9 years postoperatively. Although tinnitus persisted, the intensity was lower overall (p = 0.013)(64)

5. Etc.

B. In herbal medicine perspective
The aim of herbal treatment is to stop the symptoms of dizziness by opening up sinus and enhancing the circulation to the central nervous system ginkgo, ginger, hawthorn, and
1. Ginkgo
Gingko biloba has been used for hundreds of years to treat various disorders such as asthma, vertigo, fatigue and, tinnitus or circulatory problems. Two of the main extracts are EGb761 and LI 1370. Most pharmacological, toxicological and clinical studies have focused on the neuroprotective value of these two main extracts. Neuroprotection is a rapidly expanding area of research. This area is of particular interest due to the fact that it represents a new avenue of therapy for a frustrating disease that may progress despite optimal treatment(66).

2. Ginger 
In the study of 78 cases were randomly divided into 2 groups, of whom 40 were treated with jinger moxibustion and 38 treated with acupuncture, showed that showed a cure rate of 72.5% with a total effective rate of 97.5% in the jinger moxibustion (Ginger moxibustion) group, while 44.7% and 73.7% respectively in the acupuncture group(67).

3. Hawthorn
a. Hypotensive effects
In the investigation of Hawthorn (Crataegus laevigata) leaves, flowers and berries used by herbal practitioners in the UK to treat hypertension in conjunction with prescribed drugs indicated that this is the first randomised controlled trial to demonstrate a hypotensive effect of hawthorn in patients with diabetes takin, according to “Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial” by Walker AF, Marakis G, Simpson E, Hope JL, Robinson PA, Hassanein M, Simpson HC(68)

b. Cardiac effects
In the evaluation of the potential cardiac effects of two alcohol extracts of commercially available hawthorn found that the mechanism of cardiac activity of hawthorn is via the Na(+),K(+)-ATPase and intracellular calcium concentrations are influenced, according to “A comparison of the effects of commercially available hawthorn preparations on calcium transients of isolated cardiomyocytes” by Rodriguez ME, Poindexter BJ, Bick RJ, Dasgupta A.(69)

c. Cardiovascular disease
In the analyzing the effect of hawthorn in prevention and protection of cardiovascular disease indicated that these beneficial effects may in part be due to the presence of antioxidant flavonoid components. While a number of studies have been performed to evaluate the clinical efficacy of hawthorn, an international, multicenter, prospective clinical study including a large number of New York Heart Association (NYHA) class II/III heart failure patients is ongoing to test hawthorn‘s long-term therapeutic effects, according to “Hawthorn: potential roles in cardiovascular disease”by Chang WT, Dao J, Shao ZH.(70)

d. Hyperlipemia
in the determination of The Yishoujiangzhi (de-blood-lipid) tablets (composed of Radix Polygori Multiflori, Rhizoma Polygonati, Fructus Lycii, CrataegusPinnatifida and Cassia Tora) and its effect on Hyperlipemia found that in the treatment of 130 cases of hyperlipemia, achieving an effective rate of 87.0% in lowering serum cholesterol and 80.8% in lowering triglyceride, according to ‘Yishou jiangzhi (de-blood-lipid) tablets in the treatment of hyperlipemia” by Guan Y, Zhao S.(71)

4. Gotu kola
a. Hyperglycemia and hypertension
In the determination of the inhibitory potential of selected Malaysian plants, including pegaga (Centella asiatica) against key enzymes related to type 2 diabetes and hypertension, found that In alpha-amylase inhibition assay, the inhibitory potential was highest in pucuk ubi for both hexane (59.22%) and dichloromethane extract (54.15%). Hexane extract of pucuk ubi (95.01%) and dichloromethane extract of kacang botol (38.94%) showed the highest inhibitory potential against alpha-glucosidase, while in ACE inhibition assay, the inhibitory potential was highest in hexane extract of pegaga (48.45%) and dichloromethane extract of pucuk betik (59.77%), according to “In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension” by Loh SP, Hadira O.(72)

b. Locomotor activity
In the investigation of the asiatic acid, a triterpenoids isolated from Centellaasiatica and its inhibitory effect on acetylcholinesterase (AChE) properties, excitatory post synaptic potential (EPSP) and locomotor activity. found that asiatic acid having an effect on AChE, a selective GABA(B) receptor agonist and no sedative effect on locomotor, according to “Inhibitory effect of asiatic acid on acetylcholinesterase, excitatory post synapticpotential and locomotor activity” by Nasir MN, Abdullah J, Habsah M, Ghani RI, Rammes G.(73)

c. Cognitive effects
In the assessment of the role of “Brahmi” (Bocopa monnieri and Centellaasiatica) and its effect on the loss of memory, cognitive deficits, impaired mental function found that both plants possess neuroprotective properties, have nootropic activity with therapeutic implications for patients with memory loss. The field has witnessed exciting patent activity with most inventions aiming at either (i) improving the methods of herbal extraction or (ii) enrichment and purification of novel compounds from brahmi or (iii) providing novel synergistic formulations for therapeutics in various human ailments, according to “Exploring the role of “Brahmi” (Bocopa monnieri andCentella asiatica) in brain function and therapy” by Shinomol GK, Muralidhara, Bharath MM.(74)

d. Antioxidant capacity
In the identification of antioxidant effects of C. asiatica was exposed to various fermentations: no fermentation (0 min), partial fermentation (120 min) and full fermentation (24 h). Total phenolic content (TPC) and ferric-reducing antioxidant power (FRAP) of C. asiatica, found that C. asiatica herbal teas should be prepared at 100 °C for 10 min to obtain the optimum antioxidant capacity. Multiple brewing steps in C. asiatica herbal tea are encouraged due to the certain amount of antioxidant obtained, according to “Antioxidant capacity and phenolic composition of fermented Centella asiatica herbal teas” by Ariffin F, Heong Chew S, Bhupinder K, Karim AA, Huda N.(75)

5. Erc.

C. In Traditional Chinese medicine perspective(76)
Traditional Chinese medicine (TCM) defines vertigo is a result of the imbalance of internal organs of that can lead to phlegm production and deficiency causes of poor blood circulation and insufficient blood supply to the brain.
1. Hyperactivity of kidney yang
a. As a result of liver qi stagnation of that lead to develop of liver fire which cause damage to the liver yin
b. TCM formula:Tian Ma Gou Teng Yin(77)
b.1. Tian Ma (Rhizoma Gastrodiae Elatae, Gastrodia Rhizome) – 9g.  -calms liver, clears wind
b.2. Gou Teng (Ramulus Cum Uncis Uncariae, Gambir Vine Stems, Gambir) – 12-15g.  -calms liver, clears wind
b.3. Shi Jue Ming (Concha Haliotidis, Abolone Shell) – 18-24g  -calms liver, clears wind
b.4. Zhi Zi (Fructus Gardeniae Jasminoidis, Cape Jasmine Fruit, Gardenia) – 9g.  -clear heat, drain fire  b.5. Huang Qin (Radix Scutellariae Baicalensis, Baical Skullcap Root, Scutellaria, Scute) – 9g.  -clear heat, drain fire
b.6. Yi Mu Cao (Herba Leonuri Heterophylli, Chinese Motherwort, Leonurus) – 9-12g.  -promote blood circulation, prevents rising of blood to the head with ascending yang
b.7. Chuan Niu Xi (RadixCyathulae Officinalis Sichuan Ox Knee) – 12g.  -promotes downward movement of blood
b.8. Du Zhong (Cortex Eucommiae Ulmoidis, Eucommia Bark) – 9-12g.  -nourish liver and kidneys
b.9. Sang Ji Sheng  (Ramulus Sangjisheng, Mulberry Mistletoe Stem, Loranthus) – 9-24g.  -nourish liver and kidneys
b.10. Ye Jiao Teng  (Caulis Polygoni Multiflori) – 9-30g.  -calms spirit  Fu Shen   (Sclerotium Poriae Cocos Pararadicis, Poria Spirit) – 9-15g.  -calms spirit

2. Retention of turbid phlegm in the middle burner
a. As a result of eating too much greasy and/or sweet foods, working too much, etc. that lead to impair the ability of spleen and stomach function
b. TCM formula: Ban Xia Bai Zhu Tian Ma Tang(78)
b.1. Ban Xia (Rhizoma Pinelliae Tematae, Pinellia Rhizome) – 4.5g.  -dries dampness, transform phlegm, direct Qi downwards
b.2. Tian Ma (Rhizoma Gastrodiae Elatae, Gastrodia Rhizome) – 3g.  -transforms phlegm, clears wind, eliminates headache and dizziness
b.3. Bai Zhu (Rhizoma Atractyloids Macrocephaelae, White Atractylodes Rhizome) – 9g.  -tonify spleen, dry dampness
b.4. Ju Hong (Pars Rubra Epicarpii Citri Erythocarpae, Red Part of the Tangerine Peel) – 3g.  -regulates Qi, transform phlegm
b.5. Fu Ling (Sclerotium Poriae Cocos,China Root, Poria, Hoelen) – 3g.  -tonify spleen, drains dampness
b.6. Gan Cao (Radix Glycyrrhizae Uralensis, Licorice Root) – 1.5g.  -harmonize herbs within formula, regulates middle jiao
b.7. Sheng Jiang (Rhizoma Zingiberis Officinalis Recens, Fresh Ginger Rhizome) – 1 slice  -harmonize stomach and spleen
b.8. Da Zao (Fructus Ziziphi Jujubae, Chinese Date, Jujube) – 2 pieces  -harmonize stomach and spleen

3. Deficiency of kidney essence (yin)
a. Most case of Deficiency of kidney essence are the result of congenital deficiency, aging, or excessive stress on the kidney system
b. TCM formula: Liu Wei Di Huang Wan(79)
b.1. Shu Di Huang (Rehmanniae Glutinosae Conquitae, Rehmannia (cooked)) – 240g.  -tonify kidney yin and essense
b.2. Shan Zhu Yu (Fructus Corni Officinalis, Asiatic Comelian Cherry Fruit, Cornus) – 120g.  -nourish liver, stops essence leakage
b.3. ShanYao (Radix Dioscoreae Oppositae, Chinese Yam, Dioscorea) – 120g.  -stabilizes essence, tonify spleen
b.4. Mu Dan Pi (Cortex Moutan Radicis, Cortex of the Tree Peony Root, Moutan) – 90g.  -clears liver fire
b.5. Fu Ling (Sclerotium Poriae Cocos, China-root, Poria, Hoelen) – 90g.  -drains dampness, tonify spleen
b.6. Ze Xie (Rhizoma Alismatis Orientalitis, Water Plantain Rhizome, Alisma) – 90g.  -clears and drains kidney fire


4. Deficiency of qi and blood(80)
a. Chronic illness, massive blood loss, or chronic deficiencies of spleen and stomach function can cause the deficiency of qi and blood
b. TCM formula Guipi Tang 
b.1. Huang Qi (Radix Astragali Membranaceus, Milk Vetch Root, Astragalus) – 9-12g.  -tonify spleen Qi, tonify blood
b.2. Ren Shen (Radix Ginseng, Ginseng) – 3-6g.  -tonify spleen Qi
b.3. Bai Zhu (Rhizoma Atractyloids Macrocephaeiae, Atractylodes (white) Rhizome) – 9-12g.  -tonify spleen Qi, dries dampness
b.4. Fu Shen (Sclerotium Porae Cocos Pararadicis, Poria Spirit) – 9-12g.  -calms spirit, tonify spleen  b.5. Dang Gui (Radix Angelicae Sinensis, Chinese Angelica Root, tang-kuei) – 6-9g.  -tonify blood, regulate menstruation
b.6. Mu Xiang (Radix Aucklandiae Lappae, Costus Root, Saussurea, Aucklandia) – 3-6g.  -regulates Qi  b.7. Long Yan Rou (Arillus Euphoriae Longanae, Flesh of the Longan Fruit, Longan) – 6-9g.  -tonify blood, calm spirit
b.8. Suan Zao Ren (Semen Zizyphi Spinosae, Sour Jujube Seed, Zizyphus) – 9-12g.  -calms spirit
b.9. Yuan Zhi (Radix Polygalae Tenuifoliae, Chinese Senega root, Polygala) – 3-6g.  -calms spirit, promotes heart Qi
b.10. Zhi Gan Cao (Radix Glycyrrhizae Uralensis, Licorice Root) – 3-6g.  -tonify spleen Qi

Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve 
Optimal Health And Loose Weight

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22377855
(2) http://www.ncbi.nlm.nih.gov/pubmed/459987
(3) http://www.ncbi.nlm.nih.gov/pubmed/19987027
(4) http://www.ncbi.nlm.nih.gov/pubmed/19008741
(5) http://www.ncbi.nlm.nih.gov/pubmed/22379397
(6) http://www.ncbi.nlm.nih.gov/pubmed/21572081
(7) http://www.ncbi.nlm.nih.gov/pubmed/20162029
(8) http://www.ncbi.nlm.nih.gov/pubmed/17052426
(9) http://www.ncbi.nlm.nih.gov/pubmed/22060084
(10) http://www.ncbi.nlm.nih.gov/pubmed/19128712
(10) http://www.ncbi.nlm.nih.gov/pubmed/17986375
(11) http://www.ncbi.nlm.nih.gov/pubmed/19300597 
(12) http://www.ncbi.nlm.nih.gov/pubmed/14670144
(13) http://www.ncbi.nlm.nih.gov/pubmed/21728751
(14) http://www.ncbi.nlm.nih.gov/pubmed/22379397 
(15) http://www.ncbi.nlm.nih.gov/pubmed/22162937
(16) http://www.ncbi.nlm.nih.gov/pubmed/22219058
(17) http://www.ncbi.nlm.nih.gov/pubmed/10445080
(18) http://www.dizziness-and-balance.com/disorders/psych/psych.htm
(19) http://www.ncbi.nlm.nih.gov/pubmed/12710715
(20) http://www.ncbi.nlm.nih.gov/pubmed/2354746
(21) http://www.ncbi.nlm.nih.gov/pubmed/19932588
(22) http://www.ncbi.nlm.nih.gov/pubmed/21535797
(23) http://www.ncbi.nlm.nih.gov/pubmed/20136443
(24) http://www.ncbi.nlm.nih.gov/pubmed/6579892
(25) http://www.ncbi.nlm.nih.gov/pubmed/20394007
(26) http://www.ncbi.nlm.nih.gov/pubmed/10545673
(27) http://www.ncbi.nlm.nih.gov/pubmed/18274639
(28) http://www.ncbi.nlm.nih.gov/pubmed/20471963
(29) http://www.ncbi.nlm.nih.gov/pubmed/22027055
(30) http://www.ncbi.nlm.nih.gov/pubmed/22269864
(31) http://www.ncbi.nlm.nih.gov/pubmed/22268108
(32) http://www.ncbi.nlm.nih.gov/pubmed/22256752
(33) http://www.ncbi.nlm.nih.gov/pubmed/21662239
(34) http://www.ncbi.nlm.nih.gov/pubmed/1378087
(35) http://www.ncbi.nlm.nih.gov/pubmed/21324570
(36) http://www.ncbi.nlm.nih.gov/pubmed/18287364
(37) http://www.ncbi.nlm.nih.gov/pubmed/10544191
(38) http://the-anti-aging-guide.blogspot.ca/2011/03/anti-aging-guide.html
(39) http://www.ncbi.nlm.nih.gov/pubmed/10097895
(40) http://www.ncbi.nlm.nih.gov/pubmed/20043266
(41) http://www.ncbi.nlm.nih.gov/pubmed/19083431
(42) http://mi.rsmjournals.com/content/17/1/19.abstract
(43) http://www.ncbi.nlm.nih.gov/pubmed/21726658
(44) http://www.ncbi.nlm.nih.gov/pubmed/22128219
(45) http://www.ncbi.nlm.nih.gov/pubmed/19902983
(46)  http://www.ncbi.nlm.nih.gov/pubmed/22009132
(47) http://www.ncbi.nlm.nih.gov/pubmed/19858733
(48) http://www.ncbi.nlm.nih.gov/pubmed/19707219
(49) http://www.ncbi.nlm.nih.gov/pubmed/16008542
(50) http://www.ncbi.nlm.nih.gov/pubmed/20650344
(51) http://www.ncbi.nlm.nih.gov/pubmed/17536130
(52) http://www.ncbi.nlm.nih.gov/pubmed/11238483
(53) http://www.ncbi.nlm.nih.gov/pubmed/21560310
(54) http://www.ncbi.nlm.nih.gov/pubmed?term=Sardines%20and%20heart%20health
(55) http://www.ncbi.nlm.nih.gov/pubmed/19040594
(56) http://www.ncbi.nlm.nih.gov/pubmed/19809178
(57) http://www.ncbi.nlm.nih.gov/pubmed/22085913
(58) http://www.ncbi.nlm.nih.gov/pubmed/22509688
(59) http://www.ncbi.nlm.nih.gov/pubmed/19239952
(60) http://www.dizziness-and-balance.com/disorders/bppv/lcanalbppv.htm
(61) http://www.ncbi.nlm.nih.gov/pubmed/15378315
(62) http://www.ncbi.nlm.nih.gov/pubmed/12521357
(63) http://www.ncbi.nlm.nih.gov/pubmed/9186970
(64) http://www.ncbi.nlm.nih.gov/pubmed/22201453
(65) http://www.ncbi.nlm.nih.gov/pubmed/8172700
(66) http://www.ncbi.nlm.nih.gov/pubmed/22355250
(67) http://www.ncbi.nlm.nih.gov/pubmed/16705845
(68) http://www.ncbi.nlm.nih.gov/pubmed/16762125
(69) http://www.ncbi.nlm.nih.gov/pubmed/19053860
(70) http://www.ncbi.nlm.nih.gov/pubmed/15844828
(71) http://www.ncbi.nlm.nih.gov/pubmed/8569253
(72) http://www.ncbi.nlm.nih.gov/pubmed/22135867
(73) http://www.ncbi.nlm.nih.gov/pubmed/22112723
(74) http://www.ncbi.nlm.nih.gov/pubmed/22074576
(75) http://www.ncbi.nlm.nih.gov/pubmed/21987075
(76) http://www.itmonline.org/arts/tinmen.htm 
(77) http://www.chinesemedicinetools.com/theory/herbal-medicine/chinese-herbal-formulas-general/tian-ma-gou-teng-yin
(78) http://www.chinesemedicinetools.com/theory/herbal-medicine/chinese-herbal-formulas-general/ban-xia-bai-zhu-tian-ma-tang 
(79) http://www.chinesemedicinetools.com/theory/herbal-medicine/chinese-herbal-formulas-general/liu-wei-di-huang-wan
(80) http://www.chinesemedicinetools.com/theory/herbal-medicine/chinese-herbal-formulas-general/gui-pi-tang